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The use of a single-pass albumin dialysis (SPAD) to correct severe hyperbilirubinemia in Weil's disease: a case report

Viktor Kotarski ; Klinika za infektivne bolesti "Dr. Fran Mihaljević", Zagreb, Hrvatska
Marija Santini ; Klinika za infektivne bolesti "Dr. Fran Mihaljević", Zagreb, Hrvatska
Marko Kutleša ; Klinika za infektivne bolesti "Dr. Fran Mihaljević", Zagreb, Hrvatska
Renata Josipović ; Klinika za infektivne bolesti "Dr. Fran Mihaljević", Zagreb, Hrvatska
Anđa Novokmet ; Klinika za infektivne bolesti "Dr. Fran Mihaljević", Zagreb, Hrvatska
Tomislav Krčelić ; Klinika za infektivne bolesti "Dr. Fran Mihaljević", Zagreb, Hrvatska
Vladimir Krajinović ; Klinika za infektivne bolesti "Dr. Fran Mihaljević", Zagreb, Hrvatska
Bruno Baršić ; Klinika za infektivne bolesti "Dr. Fran Mihaljević", Zagreb, Hrvatska


Puni tekst: engleski pdf 267 Kb

str. 19-21

preuzimanja: 639

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Sažetak

Liver failure, regardless of the cause, carries a high risk of morbidity and mortality. Many of the toxins that accumulate in liver failure are poorly water-soluble and are thus transported through the bloodstream bound to albumins. Renal replacement therapy does not significantly alter the concentration of bilirubin and other albumin-bound toxins in the serum. In patients with liver failure additional detoxification methods are needed. There are several artificial extracorporeal liver support systems based on the principle of albumin but their availability is limited due to high cost and requirement of operators with special training. There have been several reports of using SPAD (single pass albumin dialysis) as an effective alternative. The main advantage of this method is that it
can be performed using conventional renal replacement therapy (RRT) devices. In this report, the authors report the use of SPAD to treat severe liver failure in a patient with Weil's disease.

Ključne riječi

leptospirosis, hyperbilirubinemia, single-pass albumin dialysis

Hrčak ID:

216062

URI

https://hrcak.srce.hr/216062

Podaci na drugim jezicima: hrvatski

Posjeta: 1.013 *