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https://doi.org/10.20471/acc.2019.58.03.07

Survival until Discharge of Very-Low-Birth-Weight Infants in Two Croatian Perinatal Care Regions: A Retrospective Cohort Study of Time and Cause of Death

Darjan Kardum ; Neonatal Intensive Care Unit, Department of Pediatrics, Osijek University Hospital Centre, Osijek, Croatia; School of Medicine, Josip Juraj Strossmayer University, Osijek, Croatia
Boris Filipović-Grčić ; Neonatal Intensive Care Unit, Department of Pediatrics, Zagreb University Hospital Centre, Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia
Andrijana Müller ; School of Medicine, Josip Juraj Strossmayer University, Osijek, Croatia; Department of Gynecology and Obstetrics, Osijek University Hospital Centre, Osijek, Croatia
Sandro Dessardo ; Neonatal and Pediatric Intensive Care Unit, Department of Pediatrics, Rijeka University Hospital Centre, Rijeka, Croatia; School of Medicine, University of Rijeka, Rijeka, Croatia

Puni tekst: engleski, pdf (433 KB) str. 446-454 preuzimanja: 98* citiraj
APA 6th Edition
Kardum, D., Filipović-Grčić, B., Müller, A. i Dessardo, S. (2019). Survival until Discharge of Very-Low-Birth-Weight Infants in Two Croatian Perinatal Care Regions: A Retrospective Cohort Study of Time and Cause of Death. Acta clinica Croatica, 58. (3.), 446-454. https://doi.org/10.20471/acc.2019.58.03.07
MLA 8th Edition
Kardum, Darjan, et al. "Survival until Discharge of Very-Low-Birth-Weight Infants in Two Croatian Perinatal Care Regions: A Retrospective Cohort Study of Time and Cause of Death." Acta clinica Croatica, vol. 58., br. 3., 2019, str. 446-454. https://doi.org/10.20471/acc.2019.58.03.07. Citirano 25.11.2020.
Chicago 17th Edition
Kardum, Darjan, Boris Filipović-Grčić, Andrijana Müller i Sandro Dessardo. "Survival until Discharge of Very-Low-Birth-Weight Infants in Two Croatian Perinatal Care Regions: A Retrospective Cohort Study of Time and Cause of Death." Acta clinica Croatica 58., br. 3. (2019): 446-454. https://doi.org/10.20471/acc.2019.58.03.07
Harvard
Kardum, D., et al. (2019). 'Survival until Discharge of Very-Low-Birth-Weight Infants in Two Croatian Perinatal Care Regions: A Retrospective Cohort Study of Time and Cause of Death', Acta clinica Croatica, 58.(3.), str. 446-454. https://doi.org/10.20471/acc.2019.58.03.07
Vancouver
Kardum D, Filipović-Grčić B, Müller A, Dessardo S. Survival until Discharge of Very-Low-Birth-Weight Infants in Two Croatian Perinatal Care Regions: A Retrospective Cohort Study of Time and Cause of Death. Acta clinica Croatica [Internet]. 2019 [pristupljeno 25.11.2020.];58.(3.):446-454. https://doi.org/10.20471/acc.2019.58.03.07
IEEE
D. Kardum, B. Filipović-Grčić, A. Müller i S. Dessardo, "Survival until Discharge of Very-Low-Birth-Weight Infants in Two Croatian Perinatal Care Regions: A Retrospective Cohort Study of Time and Cause of Death", Acta clinica Croatica, vol.58., br. 3., str. 446-454, 2019. [Online]. https://doi.org/10.20471/acc.2019.58.03.07

Sažetak
We investigated mortality, causes, timing and risk factors for death until hospital discharge in very-low-birth-weight (VLBW) infants born in two Croatian perinatal care regions. This retrospective study included 252 live born VLBW infants. The mortality rate until hospital discharge was 30.5% (77/252). VLBW in-fants who died had by 4 weeks lower gestational age (GA) than surviving infants (median GA, 25 vs. 29 weeks), lower birth weight (BW) (mean BW, 756.4 vs. 1126.4 g), lower 5-minute Apgar score (median 5 vs. 8) and were more often resuscitated at birth (41.6 vs. 19.4%; p<0.001 all). Infants who survived were more often small-for-gestational age (SGA) (28.0 vs. 15.6%; p=0.04) and more often received continuous-positive-airway-pressure (CPAP) in delivery room (13.1 vs. 2.6%; p=0.01). Multivariate logistic regression revealed that parameters influencing death until hospital discharge were 5-minute Apgar score (OR 0.780, 95% CI 0.648-0.939) and higher Clinical Risk Index for Babies (CRIB) score (OR 1.677, 95% CI 1.456-1.931). ROC analysis showed that CRIB score (AUC 0.927, sensitivity 92.2, specificity 81.1; p<0.001) was the strongest predictor of death until hospital discharge. In infants who died within 12 hours, death was most commonly attributed to immaturity and in those surviving >12 hours to necrotizing enterocolitis.

Ključne riječi
Infant, very low birth weight; Cause of death; Hospital mortality; Croatia

Hrčak ID: 230176

URI
https://hrcak.srce.hr/230176

[hrvatski]

Posjeta: 275 *