Izvorni znanstveni članak
COMPARISON OF PREOPERATIVE AND POSTOPERATIVE FINDINGS OF HISTOLOGIC TUMOR TYPES AND HISTOLOGIC GRADE IN PATIENTS WITH ENDOMETRIAL CARCINOMA
ALJOŠA MANDIĆ
orcid.org/0000-0002-6719-8694
; Sveučilište u Novom Sadu, Medicinski fakultet i Zavod za onkologiju Vojvodine, Novi Sad, Vojvodina, Srbija
TAMARA ĐURIČIĆ
; Zavod za onkologiju Vojvodine, Novi Sad, Vojvodina, Srbija
BOJANA GUTIĆ
; Sveučilište u Novom Sadu, Medicinski fakultet i Zavod za onkologiju Vojvodine, Novi Sad, Vojvodina, Srbija
IVOR KOLARSKI
; Sveučilište u Novom Sadu, Medicinski fakultet, Novi Sad, Vojvodina, Srbija
TATJANA KAPICL IVKOVIĆ
; Sveučilište u Novom Sadu, Medicinski fakultet i Zavod za onkologiju Vojvodine, Novi Sad, Vojvodina, Srbija
ZORAN NIKIN
; Sveučilište u Novom Sadu, Medicinski fakultet i Zavod za onkologiju Vojvodine, Novi Sad, Vojvodina, Srbija
Sažetak
Purpose: Our aim was to determine the degree of agreement between preoperative and postoperative histologic type/ subtype and degree of tumor differentiation, and to determine the degree of upgrading and downgrading in relation to preoperative and postoperative histopathologic findings. Methods: We analyzed data on 393 patients. Data included age, preoperative and postoperative histologic type/subtype and histologic grade of tumor. Data on 317 patients were included in statistical processing. Results: Statistical analysis showed moderate agreement between preoperative and postoperative histologic type/subtype of endometrial carcinoma and low degree of agreement between preoperative and postoperative histologic grade of tumor. The lowest agreement in histologic grade was recorded in patients with histologic grade 1 (55.04%), while most accurate agreement was found in patients with grade 3 (73.33%). There was a low degree of agreement between preoperative and postoperative histologic grade in patients with endometrioid adenocarcinoma in both cases. The lowest accuracy in the agreement of histologic grade was in G1, while grades 2 and 3 were similar in the degree of agreement. Conclusions: There is moderate agreement of preoperative and postoperative histologic type/ subtype and low agreement of preoperative and postoperative histologic grade of tumor. The lowest degree of agreement was recorded for preoperatively G1 tumors and highest for preoperatively G3 tumors, which is important because of the clinical significance of tumor histologic grade 3.
Ključne riječi
endometrial carcinoma; histologic type; histologic grade
Hrčak ID:
230808
URI
Datum izdavanja:
5.12.2019.
Posjeta: 852 *