hrcak mascot   Srce   HID

Izvorni znanstveni članak
https://doi.org/10.20471/acc.2019.58.04.08

Therapeutic Plasma Exchange and Double Filtration Plasmapheresis in Severe Neuroimmune Disorders

Corina Roman-Filip ; Lucian Blaga University, Faculty of Medicine, Sibiu, Romania; Department of Neurology, University Emergency County Hospital Sibiu, Sibiu, Romania
Maria-Gabriela Catană ; Department of Neurology, University Emergency County Hospital Sibiu, Sibiu, Romania
Alina Bereanu ; Lucian Blaga University, Faculty of Medicine, Sibiu, Romania
Ana Lăzăroae ; Department of Neurology, University Emergency County Hospital Sibiu, Sibiu, Romania
Felicia Gligor ; Lucian Blaga University, Faculty of Medicine, Sibiu, Romania
Mihai Sava ; Lucian Blaga University, Faculty of Medicine, Sibiu, Romania; Department of Anesthesia, University Emergency County Hospital Sibiu, Sibiu, Romania

Puni tekst: engleski, pdf (209 KB) str. 621-625 preuzimanja: 207* citiraj
APA 6th Edition
Roman-Filip, C., Catană, M., Bereanu, A., Lăzăroae, A., Gligor, F. i Sava, M. (2019). Therapeutic Plasma Exchange and Double Filtration Plasmapheresis in Severe Neuroimmune Disorders. Acta clinica Croatica, 58. (4.), 621-625. https://doi.org/10.20471/acc.2019.58.04.08
MLA 8th Edition
Roman-Filip, Corina, et al. "Therapeutic Plasma Exchange and Double Filtration Plasmapheresis in Severe Neuroimmune Disorders." Acta clinica Croatica, vol. 58., br. 4., 2019, str. 621-625. https://doi.org/10.20471/acc.2019.58.04.08. Citirano 04.08.2021.
Chicago 17th Edition
Roman-Filip, Corina, Maria-Gabriela Catană, Alina Bereanu, Ana Lăzăroae, Felicia Gligor i Mihai Sava. "Therapeutic Plasma Exchange and Double Filtration Plasmapheresis in Severe Neuroimmune Disorders." Acta clinica Croatica 58., br. 4. (2019): 621-625. https://doi.org/10.20471/acc.2019.58.04.08
Harvard
Roman-Filip, C., et al. (2019). 'Therapeutic Plasma Exchange and Double Filtration Plasmapheresis in Severe Neuroimmune Disorders', Acta clinica Croatica, 58.(4.), str. 621-625. https://doi.org/10.20471/acc.2019.58.04.08
Vancouver
Roman-Filip C, Catană M, Bereanu A, Lăzăroae A, Gligor F, Sava M. Therapeutic Plasma Exchange and Double Filtration Plasmapheresis in Severe Neuroimmune Disorders. Acta clinica Croatica [Internet]. 2019 [pristupljeno 04.08.2021.];58.(4.):621-625. https://doi.org/10.20471/acc.2019.58.04.08
IEEE
C. Roman-Filip, M. Catană, A. Bereanu, A. Lăzăroae, F. Gligor i M. Sava, "Therapeutic Plasma Exchange and Double Filtration Plasmapheresis in Severe Neuroimmune Disorders", Acta clinica Croatica, vol.58., br. 4., str. 621-625, 2019. [Online]. https://doi.org/10.20471/acc.2019.58.04.08

Sažetak
Therapeutic plasma exchange (TPE) is an extracorporeal blood purification technique, which removes large molecular weight particles such as autoantibodies from plasma. TPE is accepted by the American Society for Apheresis as first line treatment for some severe neuroimmune disorders. Double filtration plasmapheresis (DFPP) is a newer technique in which plasma is not entirely removed, only the antibodies, using special filters. High-dose intravenous immunoglobulins are an alternative treatment for these patients but are much more expensive. We reviewed medical records of 20 patients with severe neurological diseases requiring TPE or DFPP. We analyzed the indications, complications and efficacy of these procedures. After completing the procedures, neurological improvement was recorded in 80% of the patients, 5% had no improvement, and the mortality was 15%. The rate of neurological improvement was similar to other studies. None of the patients presented catheter related complications. Systemic complications were mild, transient and completely reversible.

Ključne riječi
Plasma exchange; Plasmapheresis; Immunoglobulins, intravenous; Autoimmune diseases of the nervous system

Hrčak ID: 235126

URI
https://hrcak.srce.hr/235126

[hrvatski]

Posjeta: 512 *