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https://doi.org/10.26332/seemedj.v4i1.130

Levels of LDL-cholesterol, Triglyceride and Urate in Patients With Type 2 Diabetes Mellitus

Dunja Šojat orcid id orcid.org/0000-0001-7269-3334 ; Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Croatia; Health Centre Osijek, Croatia
Marko Pirić orcid id orcid.org/0000-0003-0287-7861 ; Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Croatia; Health Centre Osijek, Croatia
Marja Klarić ; Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Croatia
Matej Šapina ; Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Croatia; Clinical Hospital Centre Osijek, Croatia
Zvonimir Popović orcid id orcid.org/0000-0003-3397-7726 ; Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Croatia; Clinical Hospital Centre Osijek, Croatia
Tatjana Bačun ; Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Croatia; Clinical Hospital Centre Osijek, Croatia


Puni tekst: engleski pdf 308 Kb

str. 32-39

preuzimanja: 208

citiraj


Sažetak

Aim: The study aimed to examine LDL cholesterol, triglyceride and urate levels in patients of both sexes with type 2 diabetes mellitus (DM2T) in family medicine offices and to examine whether there is a difference in these parameters between obese patients and patients with normal body weight with DM2T, and between patients with and without manifest cardiovascular diseases.

Participants and methods: The study was organized as a cross-sectional study. It included 136 participants of both sexes diagnosed with DM2T, who were divided into groups of patients with or without adiposity and into groups of patients with or without experience of cardiovascular event. General and demographic data were collected, as well as data on experiencing cardiovascular events and levels of LDL cholesterol, triglycerides and urates.

Results: The average LDL cholesterol level was 2.93 mmol/L, the average triglyceride level was 1.65 mmol/L and the average urate level was 326.36 µmol/L. Only 12.5% of participants reached target LDL cholesterol levels, while levels of triglycerides and urates were within recommended limits. 24.3% of participants had experienced cardiovascular events and 39.7% of participants were obese. There was no significant difference in levels of LDL cholesterol, triglycerides and urates in participants who had experienced a cardiovascular event and those who had not. There was a significantly higher concentration of triglycerides in obese patients than in patients with normal body weight (p = 0.005).

Conclusion: In addition to regulation of glycaemia in patients with DM2T, statin doses should be increased in order to reach the target levels of LDL cholesterol. When it comes to obese patients, education courses on physical activity and diet should be conducted more often and, if necessary, fibrates should be included in therapy in order to reduce additional cardiovascular risks.

(Šojat* D, Pirić M, Klarić M, Šapina M, Popović Z, Bačun T. Levels of LDL Cholesterol, Triglyceride and Urate in Patients With Type 2 Diabetes Mellitus. SEEMEDJ 2020; 4(1); 32-39)

Ključne riječi

type 2 diabetes; LDL cholesterol; triglycerides; urates

Hrčak ID:

237404

URI

https://hrcak.srce.hr/237404

Datum izdavanja:

27.4.2020.

Posjeta: 730 *