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Pregledni rad
https://doi.org/10.20471/LO.2020.48.01.05

Abscopal effect of radiotherapy: an old concept in a new era

Martina Mikulandra ; Division of Radiotherapy and Medical Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Iva Andrašek ; Division of Radiotherapy and Medical Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Lidija Beketić-Orešković ; Division of Radiotherapy and Medical Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; Department of Clinical Oncology, School of Medicine University of Zagreb, Zagreb, Croatia

Puni tekst: engleski, pdf (469 KB) str. 27-34 preuzimanja: 36* citiraj
APA 6th Edition
Mikulandra, M., Andrašek, I. i Beketić-Orešković, L. (2020). Abscopal effect of radiotherapy: an old concept in a new era. Libri Oncologici, 48 (1), 27-34. https://doi.org/10.20471/LO.2020.48.01.05
MLA 8th Edition
Mikulandra, Martina, et al. "Abscopal effect of radiotherapy: an old concept in a new era." Libri Oncologici, vol. 48, br. 1, 2020, str. 27-34. https://doi.org/10.20471/LO.2020.48.01.05. Citirano 29.09.2020.
Chicago 17th Edition
Mikulandra, Martina, Iva Andrašek i Lidija Beketić-Orešković. "Abscopal effect of radiotherapy: an old concept in a new era." Libri Oncologici 48, br. 1 (2020): 27-34. https://doi.org/10.20471/LO.2020.48.01.05
Harvard
Mikulandra, M., Andrašek, I., i Beketić-Orešković, L. (2020). 'Abscopal effect of radiotherapy: an old concept in a new era', Libri Oncologici, 48(1), str. 27-34. https://doi.org/10.20471/LO.2020.48.01.05
Vancouver
Mikulandra M, Andrašek I, Beketić-Orešković L. Abscopal effect of radiotherapy: an old concept in a new era. Libri Oncologici [Internet]. 2020 [pristupljeno 29.09.2020.];48(1):27-34. https://doi.org/10.20471/LO.2020.48.01.05
IEEE
M. Mikulandra, I. Andrašek i L. Beketić-Orešković, "Abscopal effect of radiotherapy: an old concept in a new era", Libri Oncologici, vol.48, br. 1, str. 27-34, 2020. [Online]. https://doi.org/10.20471/LO.2020.48.01.05

Sažetak
The abscopal effect is a phenomenon that describes the systemic antitumor response that can occur as a result of a localized radiotherapy. Although sporadic cases of abscopal effect have been reported since 1960’s, the number of reported cases are significantly increasing in the immunotherapy era. Immunotherapy seems to enhance the immunogenic effects of radiotherapy, thus increasing systemic antitumor response. Although combination of radiotherapy and immunotherapy is a promising strategy in the treatment of metastatic cancers, many questions regarding the optimal treatment remain unanswered. Increasing number of ongoing studies will hopefully provide answers to these questions, enabling the utilization of this strategy in systemic anticancer treatment.

Ključne riječi
abscopal effect; radiotherapy; immunotherapy

Hrčak ID: 240614

URI
https://hrcak.srce.hr/240614

[hrvatski]

Posjeta: 80 *