Acta clinica Croatica, Vol. 59. No. 2., 2020.
Izvorni znanstveni članak
https://doi.org/10.20471/acc.2020.59.02.09
Prognostic Value of Cranial Ultrasonography in Comparison with Magnetic Resonance Imaging in Children with Cerebral Palsy: a Population-Based Study
Sanja Delin
orcid.org/0000-0003-4388-7249
; Zadar General Hospital, Department of Pediatrics, Zadar, Croatia; School of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia
Katarina Bošnjak Nađ
; Special Hospital for Developmental Neurology and Rehabilitation, Zagreb, Croatia
Sunčica Martinec
; Krapinske Toplice Special Hospital for Medical Rehabilitation, Krapinske Toplice, Croatia
Dunja Čokolić Petrović
; Osijek University Hospital Centre, Department of Pediatrics, Osijek, Croatia
Andrea Šimić Klarić
; School of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; Požega General Hospital, Department of Pediatrics, Požega, Croatia
Vlatka Mejaški Bošnjak
; Zagreb Children’s Hospital, School of Medicine, University of Zagreb, Zagreb, Croatia
Sažetak
The aim of this population-based study was to evaluate the characteristics of cerebral palsy (CP) in relation to the predominant pattern of the Magnetic Resonance Imaging Classification System (MRI CS) that was analogously applied to the neonatal/early infant cranial ultrasound (CUS). The study included children born during the 2004-2007 period from the Croatian part (C28 RCP-HR ) of the Surveillance of Cerebral Palsy in Europe (SCPE) CP register. Motor functions, accompanying impairments and brain MRI were evaluated in 227 children, 185 of which also had CUS. Concerning CP types, 56% of children had bilateral spastic, 34% unilateral spastic, 9% dyskinetic and
1% ataxic CP type. Gross Motor Function Classification System (GMFCS) revealed that 62.05% had mild (GMFCS I-III ) and 37.85% had severe motor impairment (GMFCS IV-V). CUS showed white matter injury in 60%, gray matter injury in 12%, maldevelopments in 8%, miscellaneous changes in 14%, while 6% were normal; MRI showed significant agreement (κ=0.675, p<0.001). Neuroimaging findings of maldevelopments and predominant gray matter injury were associated with more severe CP, but 7% of children with CP had normal MRI . As we found very good agreement between CUS and MRI findings, CUS is recommended in children at an increased risk of CP if MRI is not available.
Ključne riječi
Cerebral palsy; Cranial ultrasonography; Functional classification; Magnetic resonance imaging; Surveillance of Cerebral Palsy in Europe
Hrčak ID:
243614
URI
Datum izdavanja:
1.6.2020.
Posjeta: 1.339 *