Izvorni znanstveni članak
https://doi.org/10.26332/seemedj.v4i2.141
The Histopathological Findings of Operated Tumors of the Parathyroid Glands and Patient Data: A Single Centre Experience
Ivan Feldi
orcid.org/0000-0001-6310-2205
; Faculty of Medicine, Osijek, Croatia; Department of Internal medicine, General County Hospital Našice, Croatia
Ana Jurić
; Faculty of Medicine, Osijek, Croatia
Ksenija Marjanović
; Faculty of Medicine, Osijek, Croatia; Clinical department of pathology and forensic medicine, University Hospital Centre Osijek, Osijek, Croatia
Hrvoje Mihalj
orcid.org/0000-0002-8642-073X
; Faculty of Medicine, Osijek, Croatia; Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Centre Osijek, Osijek, Croatia
Tatjana Bačun
orcid.org/0000-0001-7012-5325
; Faculty of Medicine, Osijek, Croatia; Department of Endocrinology, University Hospital Centre Osijek, Osijek, Croatia
Sažetak
Introduction: Parathyroid proliferative disorders include adenoma, hyperplasia and carcinoma. Adenoma and hyperplasia are more commonly found in women, while carcinoma, which is very rare, is equally common in both sexes. The aim of this study was to analyze parathyroid tumors location and histopathology and to compare differences between the sexes. Tumors were surgically removed at the University Hospital Centre Osijek between 2016 and 2019.
Patients and Methods: Patients of both sexes who underwent parathyroidectomy for parathyroid tumor at the University Hospital Centre Osijek between 2016 and 2019 were included in the study. Parathyroid tumor samples were histologically analyzed, and their size and histopathology were noted. Existing documentation on patients with parathyroid tumor was used. Analyses were done on archived histologic material stained with hematoxylin and eosin.
Results: Overall, 19 samples of parathyroid tumor were included in this study. Tumors of the parathyroid glands were most commonly localized on the lower left parathyroid (8 cases, 42%), and least commonly on the upper right parathyroid (2 cases, 11%). The most common disorder was adenoma (11 cases, 58%), followed by hyperplasia, while no cases of cancer were diagnosed. Women underwent tumor operations more frequently than men (17 versus 2 cases). There was no correlation between histopathology of parathyroid tumor and sex (Fisher’s exact test, p = 1) or between tumor location and sex (Fisher’s exact test, p = 1).
Conclusion: The most common locations of tumors of the parathyroid glands were the inferior glands; the most common location was the left inferior parathyroid gland and the most common disorder was adenoma. Women were operated on more frequently than men.
(Feldi I, Jurić A, Marjanović K, Mihalj H, Bačun T. The Histopathological Findings of Operated Tumors of the Parathyroid Glands and Patient Data: A Single Centre Experience. SEEMEDJ 2020; 4(2); 113-120)
Ključne riječi
parathyroid glands; primary hyperparathyroidism; histopathology; staining and labeling
Hrčak ID:
246208
URI
Datum izdavanja:
12.11.2020.
Posjeta: 553 *