Recenzija, Prikaz slučaja
Isolated vestibular dysfunction as an initial manifestation of leptomeningeal carcinomatosis due to breast cancer – A case report
Gordana Sičaja
Marija Ernoić
Hrvoje Budinčević
Sažetak
Leptomeningeal carcinomatosis is an uncommon complication of different types of cancer in which the disease spreads to meninges. It usually presents with clinical features of meningeal irritation, combined with cranial nerve involvement. This report aims to describe vestibular dysfunction as one of the possible and infrequent initial signs of leptomeningeal carcinomatosis. We present a case of a 49-year-old female that has been previously diagnosed breast cancer who developed bilateral vestibular dysfunction due to leptomeningeal carcinomatosis. Leptomeningeal carcinomatosis can be variable in its presentation since any aspect of the nervous system can be affected. Multiple cranial nerve involve- ment isn’t rare, with most commonly affected third, fifth and seventh cranial nerve (5). In our case, the patient presented with the symptoms of isolated vestibular dysfunction with preserved cochlear part
of the nerve. This can be explained by the possible way of propagation of malignant cells via endolym- phatic ductus into the inner ear with the obliterated connection between sacculus and cochlea.
Ključne riječi
leptomeningeal carcinomatosis; isolated vestibular dysfunction; breast cancer
Hrčak ID:
248906
URI
Datum izdavanja:
15.12.2020.
Posjeta: 2.789 *