Skoči na glavni sadržaj

Veterinarska stanica, Vol. 53 No. 1, 2022.

Izvorni znanstveni članak

https://doi.org/10.46419/vs.53.1.1

Interferon-α-A (IFN-α-A) Diversity in Domestic Yak (Bos grunniens) of Pakistan

Masroor Ellahi Babar ; The University of Agriculture, Dera Ismail Khan, Khyber Pakhtunkhwa, Pakistan
Tanveer Hussain ; Department of Molecular Biology, Virtual University of Pakistan, Lahore, Pakistan
Akhtar Ali ; Department of Biotechnology, Virtual University, Lahore, Pakistan
Anam Aftab ; Department of Biotechnology, Virtual University, Lahore, Pakistan
Mudassir Sohail ; Department of Livestock and Dairy Development, Gilgit Baltistan, Pakistan
Mastan Ali ; Livestock & Dairy Development Board, Gilgit Baltistan, Pakistan
Qurat ul-Ain ; Department of Biotechnology, Virtual University, Lahore, Pakistan
Abdul Wajid ; Department of Biotechnology, Virtual University, Lahore, Pakistan
Faiz Mohideen Mohamed Thassim Marikar orcid id orcid.org/0000-0003-4579-7263 ; General Sir John Kotelawala Defence University, Kandawala Estate, Ratmalana, Sri Lanka Faculty of Health Sciences, The Open University of Sri Lanka, Nawala, Sri Lanka
Muneeb Mohamed Musthafa ; Department of Biosystems Technology, Faculty of Technology, South Eastern University of Sri Lanka, University Park, Oluvil, #32360, Sri Lanka

Puni tekst: engleski pdf 617 Kb

str. 75-81

preuzimanja: 418

citiraj

Sažetak

Among the various species of livestock, the domestic yak (Bos grunniens) belongs to the class Bovidae and is specially adapted for survival at high altitudes under extreme climatic conditions. Yak is a very useful species due to the multiple products it provides, such as meat, hide, milk and other dairy products. Like other livestock species, domestic yak is also in danger of infection by microbial infections. However, multiple immunity genes encode special protein products to fight infection. One of these immunity genes is interferon-α-A (IFN-α-A), which encodes proteins that belongs to cytokines and fights
viral infections. The current study analysed the genetic variation and phylogenetic analysis of the IFN-α-A gene in domestic yak, with comparisons to other mammalian species to investigate immune diversity level, with the aim of designing molecular selection strategies for better disease resistant animals.

Ključne riječi

domestic; interferon; cytokine; infection; immunity; polymorphism

Hrčak ID:

259058

URI

https://hrcak.srce.hr/259058

Datum izdavanja:

17.6.2021.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.702 *