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Mammary Hidradenitis Suppurativa Lesions – A Suggestion for Phenotyping

Rune Kjærsgaard Andersen ; Department of Dermatology, Zealand University Hospital, Roskilde, Denmark
Jurr Boer ; Department of Dermatology, Deventer Hospital, Deventer, the Netherlands
Gregor B.E. Jemec ; Department of Dermatology, Zealand University Hospital, Roskilde, Denmark
Ditte M. Saunte ; Department of Dermatology, Zealand University Hospital, Roskilde, Denmark

Sažetak

Background: Hidradenitis suppurativa (HS) is an under-diagnosed chronic inflammatory
skin disease of the pilosebaceous unit of apocrine gland-rich parts of the
body. The mammary area is the fourth most HS-affected area and, as typical lesions
include non-fluctuating nodules, abscesses, and tunnels/sinus tracts, mammary
HS is often mistaken for other mammary “boils”, such as sub-areolar and granulomatous
non-lactating breast abscesses. Our objective was to present a spectrum of
mammary HS lesions, explore a possible classification, and expose mammary HS as
a possible differential diagnosis to non-lactational breast abscesses.
Methods: A cross-sectional study on current and newly-referred patients treated
for HS affecting the mammary area. Anamnestic information, subjective outcome
measures, and lesion counts including anatomical location were collected. Patients
with similar morphologies were grouped, and characteristics for the groups were
investigated.
Limitations: We were not aware of the number of morphologies we would find,
and as a result the study did not have sufficient power to show significant differences
after correction for multiple testing.
Results: We found three morphologically different subtypes of mammary HS; the
Sternal, the Frictional, and the Nodule types. These groups differed in anatomical
lesion characteristics and other patient characteristics. Furthermore, we found a
fourth Mixed type – a combination of the other three.
Conclusion: Differential diagnosis between mammary HS and sub-areolar or granulomatous
non-fluctuating non-lactating breast abscess is most easily performed by
assessing the precise anatomical location of the lesion and determining if the mammary
lesion is the only lesion present or if similar lesions exist in other HS-specific are

Ključne riječi

hidradenitis suppurativa, mammary lesion, morphology, non-lactating breast abscess, phenotypes, sub-types

Hrčak ID:

274454

URI

https://hrcak.srce.hr/274454

Datum izdavanja:

11.5.2021.

Posjeta: 496 *