Izvorni znanstveni članak
https://doi.org/10.3325/cmj.2020.61.422
The incidence of postural orthostatic tachycardia syndrome in the population of Zagreb, Croatia
Ivan Adamec
; Department of Neurology, Referral Center for Autonomic Nervous System Disorders, University Hospital Center Zagreb, Zagreb, Croatia
Luka Crnošija
; Department of Neurology, Referral Center for Autonomic Nervous System Disorders, University Hospital Center Zagreb, Zagreb, Croatia
Berislav Ruška
; Department of Neurology, Referral Center for Autonomic Nervous System Disorders, University Hospital Center Zagreb, Zagreb, Croatia
Tin Pavičić
; Department of Neurology, Referral Center for Autonomic Nervous System Disorders, University Hospital Center Zagreb, Zagreb, Croatia
Anamari Junaković
; Department of Neurology, Referral Center for Autonomic Nervous System Disorders, University Hospital Center Zagreb, Zagreb, Croatia
Magdalena Krbot Skorić
; Faculty of Electrical Engineering and Computing, University of Zagreb, Zagreb, Croatia
Tatjana Pekmezović
; Institute of Epidemiology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Mario Habek
; University of Zagreb School of Medicine, Zagreb, Croatia
Sažetak
Aim To estimate the incidence of postural orthostatic
tachycardia syndrome (POTS) in the population of Zagreb,
Croatia, and to determine the patients’ demographic and
clinical characteristics.
Methods From 2012-2017, we identified patients with
POTS by a retrospective analysis of medical records at University Hospital Center Zagreb. Crude incidence rates were
directly standardized by age according to the European
and World Standard Population.
Results Out of 385 patients with suspected POTS, 23 had
a definitive POTS diagnosis. The annual incidence ranged
from 3.3 to 14.8 per 1 000 000 for both sexes combined. The
highest incidence rates were in the age groups 18-29 and
30-39 years, with female predominance. The mean age at
diagnosis was 30.7 years (standard deviation ±9.2, range
18-52). The median duration of symptoms at diagnosis was
7.5 months (range 3-180 months). Regarding associated
comorbidities, two patients had chronic gastritis and one
patient had each of the following: epilepsy, prior subarachnoid hemorrhage, anxiety, mitral insufficiency, obstructive
sleep apnea, hypothyreosis, and irritable bowel syndrome.
In patients not fulfilling the criteria for POTS, the most
common alternative diagnoses were autonomic dysfunction due to multiple sclerosis in 22, anxiety disorder in 17,
epilepsy in 16, and orthostatic tachycardia due to deconditioning in 13 patients.
Conclusion The data obtained in this study can be used
to optimize disease surveillance in population, comprehensive assessment of disease burden, and organization of
health care services.
Ključne riječi
Hrčak ID:
277990
URI
Datum izdavanja:
23.10.2020.
Posjeta: 319 *