Izvorni znanstveni članak
Inverted Sinonasal Papilloma – A Report of 31 Cases and Review of the Literature
Miljenko Bura
Ivan Vladika
Gorana Aralica
Željko Bumber
Zdenko Krajina
Lana Bijelić
Gorazd Poje
Marica Žižić
Sven Seiwerth
Sažetak
Inverted papilloma is an epithelial neoplasm of the lateral nasal wall and adjacent
sinuses characterized by a marked propensity for recurrence and a significant association
with carcinoma In this retrospective study we present 31 cases treated by our departments
between 1982 and 1999. The aim was to compare our results to those of other
authors especially regarding surgical management. The male to female ratio of these
patients was 2:1 and most patients were in the 6th and 7th decades of life. Conservative
surgery was used in most cases as the initial treatment. The overall recurrence rate was
low and there were 3 cases associated with carcinoma. We conclude that the results of
conservative surgery in selected cases are comparable to those using radical methods. A
review of the literature is presented and particular attention is dedicated to the literature
concerning analysis of p53 expression, HPV and Epstein-Barr infection and apoptosis
in inverted papilloma.
Ključne riječi
head and neck tumors; nasal tumors; inverted papilloma
Hrčak ID:
28069
URI
Datum izdavanja:
16.6.2003.
Posjeta: 1.621 *