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https://doi.org/10.20471/acc.2022.61.s1.02

Blood pressure is associated with diabetic retinopathy in type 1 but not in type 2 diabetes

Tomislav Bulum orcid id orcid.org/0000-0003-4808-2968 ; Vuk Vrhovac Clinic for Diabetes, Endocrinology and Metabolic Diseases, University Hospital Merkur; Medical School, University of Zagreb, Zagreb, Croatia
Martina Tomić ; Vuk Vrhovac Clinic for Diabetes, Endocrinology and Metabolic Diseases, University Hospital Merkur
Romano Vrabec ; Vuk Vrhovac Clinic for Diabetes, Endocrinology and Metabolic Diseases, University Hospital Merkur
Miljenka Martinović Bošković ; Vuk Vrhovac Clinic for Diabetes, Endocrinology and Metabolic Diseases, University Hospital Merkur
Spomenka Ljubić ; Vuk Vrhovac Clinic for Diabetes, Endocrinology and Metabolic Diseases, University Hospital Merkur; Medical School, University of Zagreb, Zagreb, Croatia
Ingrid Prkačin ; Medical School, University of Zagreb, Zagreb, Croatia; Department of Internal Medicine, Merkur University Hospital, Zagreb, Croatia


Puni tekst: engleski pdf 1.607 Kb

verzije

str. 14-22

preuzimanja: 272

citiraj


Sažetak

The aim of this study was to investigate the role of systolic blood pressure (SBP)
and diastolic blood pressure (DBP) in the development of diabetic retinopathy (DR) in type 1 and
type 2 diabetes and to determine the differences between these two types of diabetes. This cross-sectional
study included 84 patients with type 1 diabetes (T1DM) and 107 patients with type 2 diabetes
(T2DM). Ophthalmologic retinal examination included indirect slit-lamp fundoscopy, color fundus
photography according to EURODIAB (EUROpe and DIABetes) protocol and optical coherence
tomography. Blood pressure was measured with a mercury sphygmomanometer after a 10-minute rest
period. In T1DM, DR was positively associated with SBP (p = 0.035), HbA1cmedian (p < 0.001) and
hypertensive retinopathy (p < 0.001), while in T2DM DR was positively related only to HbA1cmedian
(p = 0.021). Binary logistic regression analysis (no DR/DR) showed that diabetes duration and
HbA1cmedian were the main predictors of DR in both types of diabetes. In contrast, SBP (OR = 1.05,
p = 0.045) and hypertensive retinopathy (OR = 3.75, p < 0.001) were the main predictors/indicators
of DR only in T1DM. In conclusion, blood pressure is associated with DR in type 1 but not in type 2
diabetes.

Ključne riječi

blood pressure; type 1 and type 2 diabetes; retinopathy; risk factors

Hrčak ID:

281144

URI

https://hrcak.srce.hr/281144

Datum izdavanja:

1.6.2022.

Podaci na drugim jezicima: hrvatski

Posjeta: 977 *