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https://doi.org/10.20471/acc.2022.61.s1.02

Blood pressure is associated with diabetic retinopathy in type 1 but not in type 2 diabetes

Tomislav Bulum orcid id orcid.org/0000-0003-4808-2968 ; Vuk Vrhovac Clinic for Diabetes, Endocrinology and Metabolic Diseases, University Hospital Merkur; Medical School, University of Zagreb, Zagreb, Croatia
Martina Tomić ; Vuk Vrhovac Clinic for Diabetes, Endocrinology and Metabolic Diseases, University Hospital Merkur
Romano Vrabec ; Vuk Vrhovac Clinic for Diabetes, Endocrinology and Metabolic Diseases, University Hospital Merkur
Miljenka Martinović Bošković ; Vuk Vrhovac Clinic for Diabetes, Endocrinology and Metabolic Diseases, University Hospital Merkur
Spomenka Ljubić ; Vuk Vrhovac Clinic for Diabetes, Endocrinology and Metabolic Diseases, University Hospital Merkur; Medical School, University of Zagreb, Zagreb, Croatia
Ingrid Prkačin ; Medical School, University of Zagreb, Zagreb, Croatia; Department of Internal Medicine, Merkur University Hospital, Zagreb, Croatia


Puni tekst: engleski pdf 1.607 Kb

str. 14-22

preuzimanja: 251

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Sažetak

The aim of this study was to investigate the role of systolic blood pressure (SBP)
and diastolic blood pressure (DBP) in the development of diabetic retinopathy (DR) in type 1 and
type 2 diabetes and to determine the differences between these two types of diabetes. This cross-sectional
study included 84 patients with type 1 diabetes (T1DM) and 107 patients with type 2 diabetes
(T2DM). Ophthalmologic retinal examination included indirect slit-lamp fundoscopy, color fundus
photography according to EURODIAB (EUROpe and DIABetes) protocol and optical coherence
tomography. Blood pressure was measured with a mercury sphygmomanometer after a 10-minute rest
period. In T1DM, DR was positively associated with SBP (p = 0.035), HbA1cmedian (p < 0.001) and
hypertensive retinopathy (p < 0.001), while in T2DM DR was positively related only to HbA1cmedian
(p = 0.021). Binary logistic regression analysis (no DR/DR) showed that diabetes duration and
HbA1cmedian were the main predictors of DR in both types of diabetes. In contrast, SBP (OR = 1.05,
p = 0.045) and hypertensive retinopathy (OR = 3.75, p < 0.001) were the main predictors/indicators
of DR only in T1DM. In conclusion, blood pressure is associated with DR in type 1 but not in type 2
diabetes.

Ključne riječi

blood pressure; type 1 and type 2 diabetes; retinopathy; risk factors

Hrčak ID:

281144

URI

https://hrcak.srce.hr/281144

Datum izdavanja:

1.6.2022.

Podaci na drugim jezicima: hrvatski

Posjeta: 912 *