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Prothrombin Complex Concentrate in Emergency Department

Višnja Nesek Adam orcid id ; Emergency Department, Clinical Hospital Sveti Duh, Zagreb, Croatia; Faculty of Dental Medicine and Health, Osijek, Croatia; Libertas Interantional University, Zagreb, Croatia
Ingrid Bošan-Kilibarda ; Croatian Institute for Emergency Medicine, Croatia

Puni tekst: engleski pdf 1.375 Kb


str. 53-57

preuzimanja: 284



Coagulation abnormalities are common in bleeding or critically ill patient and
hemostatic management remains a major challenge for the emergency physician. Management of
bleeding patients consists of bleeding control, restoration of blood volume, and correction of any associated
coagulopathy. Traditionally, the fresh frozen plasma (FFP) is used for correction of coagulopathy
to manage and prevent bleeding, but today Prothrombin complex concentrates (PCCs) offer
an attractive alternative because they offers a number of advantages over FFP, including lower infusion
volume, rapid IN R normalization, faster availability, lack of blood group specificity, and better
safety profile. The aim of the present review is to provide an short overview about using PCC, their
indication, efficacy and safety in different bleeding setting’s.

Ključne riječi

bleeding; emergency department; prothrombin complex concentrates

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Datum izdavanja:


Podaci na drugim jezicima: hrvatski

Posjeta: 964 *