Pregledni rad

Cerebrospinal fluid phosphorylated tau proteins as predictors of Alzheimer’s disease in subjects with mild cognitive impairment

Goran Šimić orcid.org/0000-0002-6339-9261 ; Medicinski fakultet i Hrv. institut za istraživanje mozga Sveučilišta u Zagrebu, Zagreb, Hrvatska
Marina Boban ; Klinički bolnički centar Zagreb-Rebro, Zagreb, Hrvatska
Patrick R. Hof ; Mount Sinai School of Medicine, New York, NY 10029, U.S.A.

Sažetak

Major efforts are under way to define reliable biomarkers of Alzheimer’s disease. Highly significant increases of hyperphosphorylated tau proteins in cerebrospinal fluid have been recently reported in Alzheimer’s disease patients compared to controls by several independent groups, including ours. These findings support the notion that cerebrospinal fluid phosphorylated
tau proteins may be very useful biomarkers in the early identification of Alzheimer’s disease in patients with mild cognitive impairment.

Ključne riječi

Hrčak ID:

29049

URI

https://hrcak.srce.hr/29049

Datum izdavanja:

29.2.2008.

Posjeta: 1.672 *