Book review

https://doi.org/10.20471/acc.2022.61.04.21

Successfully Treated Acute Interstitial Pneumonia

Marija Gomerčić Palčić ; Sestre milosrdnice University Hospital Center, Zagreb; Croatia; University of Zagreb, School of Medicine, Zagreb, Croatia
Ivan Turalija ; Sestre milosrdnice University Hospital Center, Zagreb; Croatia
Luka Vrbanić ; Sestre milosrdnice University Hospital Center, Zagreb; Croatia
Ivana Folnožić ; Sestre milosrdnice University Hospital Center, Zagreb; Croatia
Eugenija Basioli Kasap ; Zadar General Hospital, Zadar, Croatia
Monika Ulamec ; Sestre milosrdnice University Hospital Center, Zagreb; Croatia; University of Zagreb, School of Medicine, Zagreb, Croatia

Abstract

Acute interstitial pneumonia (AIP) is a rare idiopathic interstitial pneumonia with
histology finding of diffuse alveolar damage (DAD). It is characterized by progressive hypoxic respiratory
failure, high mortality rate, and absence of guidelines for its treatment. Here we present a case of
a 64-year-old woman with progressive dyspnea, acute respiratory failure, diffuse bilateral reticulonodular
opacities on standard chest radiograph, diffuse ground-glass opacities on computed tomography,
and biopsy proven DAD. Diagnosis of AIP was established after extensive work-up that excluded the
known risk factors for acute respiratory distress syndrome. Oxygen therapy and high-dose parenteral
corticosteroids led to gradual improvement and resulted in complete respiratory recovery. Since there
are no existing guidelines for treating AIP, more case reports and case series if not randomized control
trials are warranted in order to define the most effective therapeutic modality.

Keywords

Acute interstitial pneumonia; Corticosteroid therapy; Acute respiratory distress syndrome; High-flow nasal cannula

Hrčak ID:

302078

URI

https://hrcak.srce.hr/302078

Publication date:

1.12.2022.

Article data in other languages: croatian

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