Izvorni znanstveni članak
https://doi.org/10.20471/acc.2023.62.s2.3
Open Radical Cystectomy: Single Center Results and Outcomes in the Last Five Years
Bojan Čikić
; Zagreb University Hospital Center, Department of Urology, Zagreb, Croatia
Toni Zekulić
orcid.org/0000-0002-3498-0217
; Zagreb University Hospital Center, Department of Urology, Zagreb, Croatia
*
Luka Penezić
; Zagreb University Hospital Center, Department of Urology, Zagreb, Croatia
Jerko Anđelić
; Zagreb University Hospital Center, Department of Urology, Zagreb, Croatia
Tomislav Kuliš
; Zagreb University Hospital Center, Department of Urology, Zagreb, Croatia; University of Zagreb, School of Medicine, Zagreb, Croatia
Hrvoje Saić
; Zagreb University Hospital Center, Department of Urology, Zagreb, Croatia
Ahmad El-Saleh
; Zagreb University Hospital Center, Department of Urology, Zagreb, Croatia
Vedran Andrijašević
; Zagreb University Hospital Center, Department of Urology, Zagreb, Croatia
Tvrtko Hudolin
; Zagreb University Hospital Center, Department of Urology, Zagreb, Croatia; University of Zagreb, School of Medicine, Zagreb, Croatia
Eleonora Goluža
; University of Zagreb, School of Medicine, Zagreb, Croatia; Zagreb University Hospital Center, Department of Anesthesiology and ICU, Zagreb, Croatia
Željko Kaštelan
; Zagreb University Hospital Center, Department of Urology, Zagreb, Croatia; University of Zagreb, School of Medicine, Zagreb, Croatia
* Dopisni autor.
Sažetak
Radical cystectomy is a therapeutic modality of choice for many patients with muscle-
invasive bladder cancer. We conducted a retrospective study of open radical cystectomies performed
at a single Center from January 2017 to January 2022. Decision on the urinary diversion type was based
on tumor stage, comorbidities, patient age, general condition and preferences. There were 19.5% of female
and 80.5% of male patients, median age 67 (range 38-90) years. We performed 96 (44.7%) ureterocutaneostomies
(UCS), 67 (31.2%) ileal conduit derivations, and 52 (24.2%) orthotopic neobladder
derivations (OND). There were 17 (7.9%) complications after UCS, 7 (3.2%) after incontinent urinary
diversion, and 7 (3.2%) after OND. Fifty-five (25.6%) patients developed early complications, of which
31 (14.4%) during the initial hospitalization period, and 24 (11.2%) required re-hospitalization in the
30-day postoperative period. The most common wound-related complication was wound dehiscence,
most typically caused by infection. The main reason for readmission was urosepsis. The 30-day mortality
rate was 0.9%. Late complications that occurred 30 days after the operation were found in 39 (18.1%)
cases. Bladder cancer is a high-mortality disease that requires a multidisciplinary and personalized approach.
Further development of multidisciplinary teams, perioperative and postoperative care, and follow-
up strategy is needed to improve the oncologic and functional outcomes of this procedure.
Ključne riječi
ystectomy; Urinary diversion; Bladder cancer; Ileal conduit; Survival
Hrčak ID:
308928
URI
Datum izdavanja:
31.7.2023.
Posjeta: 960 *