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Sažetak sa skupa

https://doi.org/10.26800/LV-145-supl8-15

A rare case of hereditary thrombotic thrombocytopenic purpura in a toddler

Ozana Jakšić
Jana Jelčić
Maša Davidović


Puni tekst: engleski pdf 234 Kb

str. 24-24

preuzimanja: 137

citiraj


Sažetak

Hereditary thrombotic thrombocytopenic purpura (hTTP) is a thrombotic microangiopathy caused by pathogenic variants in the ADAMTS13 gene resulting in highly reduced activity of von Willebrand factor-cleaving metalloprotease. hTTP is characterized by systemic for-mation of platelet-rich thrombi in microvasculature resulting in organ ischemia, throm-bocytopenia, and microangiopathic hemolytic anemia.

Ključne riječi

ADAMTS13 protease, pediatrics, thrombotic thrombocytopenic purpura

Hrčak ID:

314111

URI

https://hrcak.srce.hr/314111

Datum izdavanja:

22.2.2024.

Posjeta: 424 *