Izvorni znanstveni članak
https://doi.org/10.20471/LO.2023.51.02-03.13
Effects of hydrogen-rich water on hamsters with experimental myeloid tumor
Reneta Toshkova
; Institute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences, Sofia, Bulgaria
Nikolai Neshev
; Faculty of Physics, Sofia University St. Kliment Ohridski, Sofia, Bulgaria
Ignat Ignatov
; Scientific Research Center of Medical Biophysics (SRCMB), Sofia, Bulgaria
*
Fabio Huether
; Evodrop AG, Zürich, Switzerland
Alexander I. Ignatov
; Scientific Research Center of Medical Biophysics (SRCMB), Sofia, Bulgaria
Ivan Angushev
; Medical University-Sofia, Sofia, Bulgaria
* Dopisni autor.
Sažetak
This paper presents the results of an in vivo study of the antitumor effect of hydrogen-rich water in hamsters with experimental myeloid tumors. Hydrogen-rich EVOdrop water (HEW) with a molecular hydrogen (H2) concentration of 1.2 ppm. pH=7.3, and oxidation-reduction potential (ORP) of (-390 mV) as basic parameters were obtained with the EVObooster apparatus. The myeloid tumor was implanted subcutaneously on the back of Golden Syrian hamsters used for the experiment. The effect of HEW on biometric parameters of tumor growth, namely 18 hematological parameters and some hematological biomarkers (indices) was evaluated. The blood sera from experimental and control animals were analyzed using the Non-equilibrium energy spectrum (NES) and the Differential non-equilibrium energy spectrum (DNES) spectral methods. The results showed a protective antitumor effect of HEW seen by a decrease in tumor uptake rate, a decrease in mortality, an increase in survival time, a normalizing effect on hematological parameters and biomarkers (N/LR, WBC/LR, PLT/LR), and an increase in energy between water molecules in blood serum in hamsters with experimental myeloid tumor. The results show that HEW has anticancer potential that could be used with conventional chemotherapeutics to develop new treatment strategies as well as cancer prevention.
Ključne riječi
hydrogen-rich water; myeloid tumor; NES and DNES spectral analyses
Hrčak ID:
314271
URI
Datum izdavanja:
12.2.2024.
Posjeta: 861 *