Izvorni znanstveni članak
https://doi.org/10.20471/acc.2024.63.03-04.07
Clinical Evaluation, Diagnosis and Treatment of Pheochromocytoma
Romana Marušić
; School of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia
Tajana Turk
; School of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; Department of Radiology, Osijek University Hospital Center, Osijek, Croatia
Tatjana Bačun
; School of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; Department of Internal Medicine, Osijek University Hospital Center, Osijek, Croatia
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* Dopisni autor.
Sažetak
Pheochromocytomas are rare neuroendocrine tumors that originate in chromaffin
cells of the adrenal medulla and excessively secrete catecholamines, which leads to a multitude of different
symptoms. The most common symptoms include headaches, palpitations, and sweating. Because
of a diverse clinical presentation, pheochromocytomas pose a major diagnostic challenge and often go
unidentified. These tumors can occur sporadically or as a part of hereditary syndromes. The diagnosis
is confirmed by measuring plasma and 24-hour urinary metanephrine and normetanephrine. Computed
tomography, magnetic resonance imaging, and functional morphological examinations are used for
tumor localization. The treatment is operative and requires special preoperative patient preparation to
prevent hypertensive crisis and arrhythmias. Due to the possibility of recurrence, the patient needs to
be monitored. Pheochromocytoma has a high fatality rate if not recognized on time due to the effect of
catecholamines on the cardiovascular system.
Ključne riječi
Pheochromocytoma; Headache; Multiple endocrine neoplasia type 2; Palpitations; Paroxysmal hypertension
Hrčak ID:
333039
URI
Datum izdavanja:
31.12.2024.
Posjeta: 1.266 *