Izvorni znanstveni članak
https://doi.org/10.20471/acc.2024.63.03-04.30
Esophageal Diameter on High-Resolution Computed Tomography – a Potential Useful Marker for Interstitial Lung Disease Severity in Patients with Systemic Sclerosis
Anja Ljilja Posavec
; Special Hospital for Pulmonary Diseases, Zagreb, Croatia
Lea Šalamon
; Division of Clinical Immunology, Allergology and Rheumatology, Department of Internal Medicine, Dubrava University Hospital, Zagreb, Croatia
Renata Huzjan Korunić
; Zagreb-Centar Health Center, Zagreb, Croatia
Nevenka Piskač Živković
; Radiochirurgia Special Hospital, Zagreb, Croatia; Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia
Joško Mitrović
; Division of Clinical Immunology, Allergology and Rheumatology, Department of Internal Medicine, Dubrava University Hospital, Zagreb, Croatia; Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia
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* Dopisni autor.
Sažetak
Patients with systemic sclerosis (SSc) are at an increased risk of developing interstitial
lung disease (ILD) and esophageal dysfunction, with frequently present esophageal dilatation. Our
study aimed to investigate the relationship between esophageal diameter (ED) analyzed on high-resolution
computed tomography (HRCT) with lung function tests and ILD evaluated with Warrick score.
Thirty-nine patients with SSc were enrolled in this study. ED and Warrick score were evaluated by
HRCT. The relationships between Warrick score, lung function, and ED were analyzed. Multivariate regression
analysis was used to determine the effect of individual predictors on SSc-ILD. ILD was present
in 25 (64%) patients. ED >10 mm in one or more of the measured locations on HRCT was present in 25
(64%) patients and 19 (76%) of these patients had concurrent ILD. Subjects with esophageal dilatation
had a higher Warrick score and lower lung function tests. The measurement of ED was able to predict
the presence of ILD in 69% of patients. Results suggest that evaluation of ED during regular HRCT
follow-up could be useful in patients with SSc due to the association of esophageal dilatation with worse
lung function tests and a more severe form of ILD.
Ključne riječi
Systemic sclerosis; Esophagus; Lung diseases, interstitial; Computed tomography; Lung function tests
Hrčak ID:
333288
URI
Datum izdavanja:
31.12.2024.
Posjeta: 620 *