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Vascular Endothelial Growth Factor in Aqueous Humor of Patients with Perforative Eye Injuries

Maja Merlak
Damir Kovačević
Tihomir Balog
Tanja Marotti
Renata Grčetić Lenac
Ivana Romac
Iva Dekaris


Puni tekst: engleski pdf 125 Kb

str. 33-37

preuzimanja: 454

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Sažetak

Considering that VEGF is the key factor for angiogenesis stimulation, we wanted to establish if VEGF level is increased
in aqueous humor of patients with open globe eye injury. The study included 20 patients with open globe injury.
During the surgery, aqueous humor samples were taken out and VEGF levels were measured by ELISA. VEGF levels
were significantly higher in the aqueous humor of patients with open globe eye injury and uveitis, in patients with
wound bigger than 2 mm and in patients where from injury to surgery passed more than 4 hours. VEGF levels were also
higher, but not significantly, in patients with intrabulbar foreign body. Considering that VEGF levels were significantly
higher in patients with open globe eye injury with uveitis, wound larger than 2 mm and in patients where from injury to
surgery passed more than 4 hours, anti VEGF therapy might have application in these conditions.

Ključne riječi

vascular endothelial growth factor; aqueous humor; perforative eye injury

Hrčak ID:

34536

URI

https://hrcak.srce.hr/34536

Datum izdavanja:

1.10.2008.

Posjeta: 843 *