Izvorni znanstveni članak
GROWTH AND METAMORPHOSIS IN TADPOLES OF RANA PRETIOSA PRETIOSA, TREATED WITH RECOMBINANT PORCINE GROWTH HORMONE, PROLACTIN, SOMATOSTATIN (SRIF) AND ANTI-SRIF
Ewen McLean
; Aalborg University, Biotechnology Laboratory, Sohngaardsholmsvej 57, 9000 Aalborg, Denmark. Tel: +45 96 35 84 66; Fax: +45 98 14 25 55
I. Mayer
; University of Stockholm, Department of Zoology, S-106 91, Stockholm, Sweden.
T. J. Kieffer
; Harvard Medical School, Laboratory of Molecular Endocrinology. Massachusetts General Hospital, 32 Fruit St., WEL 320, Boston, Mass. 02114, USA.
E. M. Donaldson
; Department of Fisheries and Oceans, West Vancouver Laboratory, 4160 Marine Drive, West Vancouver, B. C., V7V 1N6, Canada.
L. M. Souza
; Amgen Inc., 1900 Oak Terrace Avenue, Thousand Oaks, CA., USA.
Sažetak
The effect of prolactin (PRL), growth hormone (GH), somatostatin (SRIF) and anti-SRIF (αSRIF) treatment upon growth and metamorphosis of western spotted frog tadpoles, T a y l o r and K o l l r o s (1946) stage (TK st.) XVI (n = 18/group) was examined. Treated animals received 2.5 g protein/g body weight every 5 days until one group exhibited > TK st. XXIV and complete terrestrialization. Administration of GH and PRL resulted in 18/18 and 15/18 animals respectively expressing complete terrestrialization. 12/18 SRIF injected tadpoles achieved > TK st. XXIV. In contrast, only 5 each of control and SRIF treated tadpoles transformed to > st. XXIV. Significantly higher (P<0.05) length: weight ratios were recorded for control versus all other treatment groups. PRL and αSRIF treated animals exhibited reduced body length: fore limb length ratios (P<0.05) when compared to controls. Greater hind-limb length was noted in animals treated with GH, SRIF and PRL. PRL treatment resulted in significantly increased length and weight (P<0.05) when compared to controls, and highly significant (P<0.01) reduction in condition factor compared against all other treatment groups.
Ključne riječi
Rana pretiosa pretiosa; metamorphosis; anti-somatostatin; somatostatin; prolactin; growth; growth hormone
Hrčak ID:
39313
URI
Datum izdavanja:
1.7.1998.
Posjeta: 3.281 *