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Acute Phase Proteins in Psoriasis

Darko Biljan ; Department of Dermatovenerology, University Hospital »Osijek«, Osijek, Croatia
Mirna Šitum ; Department of Dermatovenerology, University Hospital »Sestre Milosrdnice«, Zagreb, Croatia
Krešimir Kostović ; Department of Dermatovenerology, University Hospital Center »Zagreb», Zagreb, Croatia
Tanja Batinac ; Department of Dermatovenerology, University Hospital »Rijeka«, Rijeka, Croatia
Danica Matišić ; Laboratory for Protein and Enzyme Biochemistry, University Hospital Center »Zagreb«, Zagreb, Croatia

Puni tekst: engleski, pdf (57 KB) str. 83-86 preuzimanja: 393* citiraj
APA 6th Edition
Biljan, D., Šitum, M., Kostović, K., Batinac, T. i Matišić, D. (2009). Acute Phase Proteins in Psoriasis. Collegium antropologicum, 33 (1), 83-86. Preuzeto s https://hrcak.srce.hr/39535
MLA 8th Edition
Biljan, Darko, et al. "Acute Phase Proteins in Psoriasis." Collegium antropologicum, vol. 33, br. 1, 2009, str. 83-86. https://hrcak.srce.hr/39535. Citirano 04.07.2020.
Chicago 17th Edition
Biljan, Darko, Mirna Šitum, Krešimir Kostović, Tanja Batinac i Danica Matišić. "Acute Phase Proteins in Psoriasis." Collegium antropologicum 33, br. 1 (2009): 83-86. https://hrcak.srce.hr/39535
Harvard
Biljan, D., et al. (2009). 'Acute Phase Proteins in Psoriasis', Collegium antropologicum, 33(1), str. 83-86. Preuzeto s: https://hrcak.srce.hr/39535 (Datum pristupa: 04.07.2020.)
Vancouver
Biljan D, Šitum M, Kostović K, Batinac T, Matišić D. Acute Phase Proteins in Psoriasis. Collegium antropologicum [Internet]. 2009 [pristupljeno 04.07.2020.];33(1):83-86. Dostupno na: https://hrcak.srce.hr/39535
IEEE
D. Biljan, M. Šitum, K. Kostović, T. Batinac i D. Matišić, "Acute Phase Proteins in Psoriasis", Collegium antropologicum, vol.33, br. 1, str. 83-86, 2009. [Online]. Dostupno na: https://hrcak.srce.hr/39535. [Citirano: 04.07.2020.]

Sažetak
Psoriasis is a chronic, relapsing, inflammatory and hyperproliferative skin disorder. The levels of acute phase proteins are suggested to be elevated in those patients with acute disease. The expression of selected acute phase proteins as the parameters of humoral immunity has been analyzed in 70 patients with acute psoriasis and 40 healthy controls. The aim was to evaluate the inflammatory response in the exacerbation of psoriasis and to determine the correlation of these objective inflammatory parameters with clinical features of disease activity. Main demographic and epidemiologic features were, as well, analysed. The plasma levels of C-reactive protein (CRP) (c2 = 23.61; p<0.005), and alpha1-acid glycoprotein (a1-AGP) (c2 = 7.,42; p<0.01) were significantly increased in those patients with acute phase of the disease compared to healthy controls. Our results suggest that psoriasis is an inflammatory disease and therefore its worsening seemed to be linked to the increase in the inflammatory response. It seems that CRP and al-AGP levels could serve as important prognostic factors for the worsening of psoriasis.

Ključne riječi
alpha1-acid glycoprotein; alpha2-macroglobulin; alpha1-antitrypsin; C-reactive protein; psoriasis

Hrčak ID: 39535

URI
https://hrcak.srce.hr/39535

Posjeta: 658 *