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Dissolution of celecoxib from mucoadhesive disks based on polyaspartamide derivatives

DAVORKA BALLIAN KRZNAR
JELENA FILIPOVIĆ-GRČIĆ
BRANKA ZORC
MARIJANA ZOVKO

Puni tekst: engleski, pdf (93 KB) str. 463-471 preuzimanja: 665* citiraj
APA 6th Edition
BALLIAN KRZNAR, D., FILIPOVIĆ-GRČIĆ, J., ZORC, B. i ZOVKO, M. (2006). Dissolution of celecoxib from mucoadhesive disks based on polyaspartamide derivatives. Acta Pharmaceutica, 56 (4), 463-471. Preuzeto s https://hrcak.srce.hr/4608
MLA 8th Edition
BALLIAN KRZNAR, DAVORKA, et al. "Dissolution of celecoxib from mucoadhesive disks based on polyaspartamide derivatives." Acta Pharmaceutica, vol. 56, br. 4, 2006, str. 463-471. https://hrcak.srce.hr/4608. Citirano 17.11.2019.
Chicago 17th Edition
BALLIAN KRZNAR, DAVORKA, JELENA FILIPOVIĆ-GRČIĆ, BRANKA ZORC i MARIJANA ZOVKO. "Dissolution of celecoxib from mucoadhesive disks based on polyaspartamide derivatives." Acta Pharmaceutica 56, br. 4 (2006): 463-471. https://hrcak.srce.hr/4608
Harvard
BALLIAN KRZNAR, D., et al. (2006). 'Dissolution of celecoxib from mucoadhesive disks based on polyaspartamide derivatives', Acta Pharmaceutica, 56(4), str. 463-471. Preuzeto s: https://hrcak.srce.hr/4608 (Datum pristupa: 17.11.2019.)
Vancouver
BALLIAN KRZNAR D, FILIPOVIĆ-GRČIĆ J, ZORC B, ZOVKO M. Dissolution of celecoxib from mucoadhesive disks based on polyaspartamide derivatives. Acta Pharm. [Internet]. 2006 [pristupljeno 17.11.2019.];56(4):463-471. Dostupno na: https://hrcak.srce.hr/4608
IEEE
D. BALLIAN KRZNAR, J. FILIPOVIĆ-GRČIĆ, B. ZORC i M. ZOVKO, "Dissolution of celecoxib from mucoadhesive disks based on polyaspartamide derivatives", Acta Pharmaceutica, vol.56, br. 4, str. 463-471, 2006. [Online]. Dostupno na: https://hrcak.srce.hr/4608. [Citirano: 17.11.2019.]

Sažetak
A series of mucoadhesive disks with celecoxib as a model drug of very low aqueous solubility were prepared and characterized. Two polymers of polyaspartamide type, poly,-(N-2-hydroxyethyl-DL-aspartamide) (PHEA, 1) and its thiolated analogue poly[α,β-(N-2-hydroxyethyl-DL-aspartamide)]-poly[α,β-(N-2-thioethyl-DL-aspartamide)] copolymer (PHTA, 2a,b), and two commercially available polymers Carbopol 934P and hydroxypropylmethyl cellulose 4000 were used as excipients. Disks containing a mixture of equivalent amounts of thiomer 2b and Carbopol 934P as an excipient exhibited the highest dissolution rate.

Ključne riječi
celecoxib; disks; polyaspartamide; thiomer

Hrčak ID: 4608

URI
https://hrcak.srce.hr/4608

[hrvatski]

Posjeta: 960 *