Acta Pharmaceutica, Vol. 56 No. 4, 2006.
Izvorni znanstveni članak
Quality assessment of the procedure for determination of heavy metals on reactive carriers
JADRANKA VUKOVIĆ
VLADIMIR GRDINIĆ
RENATA JURIŠIĆ GRUBEŠIĆ
OGNJEN ŽUPANIĆ
Sažetak
Quality control and validity check of the solid-phase spectrophotometric procedure (Me-SPS) for determination of heavy metals important in pharmaceutical practice: zinc (Zn-SPS), lead (Pb-SPS), and cobalt (Co-SPS) were performed using a very simple and informative prevalidation concept. Further, metrological characteristics of the Me-SPS procedure together with the diagnosis of particular prevalidation steps were evaluated. Favourable prevalidation characteristics, i.e., ideal analytical function, homogeneity of data material, low limit of quantitation, and acceptable accuracy verified the quality of the Me-SPS procedure and pointed to the limitations of some investigated systems.
Ključne riječi
analytical procedure quality control; prevalidation strategy; heavy metals; solid-phase spectrophotometry
Hrčak ID:
4613
URI
Datum izdavanja:
1.12.2006.
Posjeta: 1.328 *