Thallium Toxicity in Humans
; Department of Molecular Biology, Faculty of Science, University of Zagreb, Zagreb, Croatia
Ivan Cvjetko ; University Hospital Merkur, Medical School, University of Zagreb, Zagreb, Croatia
Mirjana Pavlica ; Department of Molecular Biology, Faculty of Science, University of Zagreb, Zagreb, Croatia
APA 6th Edition
Cvjetko, P., Cvjetko, I. i Pavlica, M. (2010). Thallium Toxicity in Humans. Arhiv za higijenu rada i toksikologiju, 61 (1), 111-118. https://doi.org/10.2478/10004-1254-61-2010-1976
MLA 8th Edition
Cvjetko, Petra, et al. "Thallium Toxicity in Humans." Arhiv za higijenu rada i toksikologiju, vol. 61, br. 1, 2010, str. 111-118. https://doi.org/10.2478/10004-1254-61-2010-1976. Citirano 14.08.2022.
Chicago 17th Edition
Cvjetko, Petra, Ivan Cvjetko i Mirjana Pavlica. "Thallium Toxicity in Humans." Arhiv za higijenu rada i toksikologiju 61, br. 1 (2010): 111-118. https://doi.org/10.2478/10004-1254-61-2010-1976
Cvjetko, P., Cvjetko, I., i Pavlica, M. (2010). 'Thallium Toxicity in Humans', Arhiv za higijenu rada i toksikologiju, 61(1), str. 111-118. https://doi.org/10.2478/10004-1254-61-2010-1976
Cvjetko P, Cvjetko I, Pavlica M. Thallium Toxicity in Humans. Arh Hig Rada Toksikol. [Internet]. 2010 [pristupljeno 14.08.2022.];61(1):111-118. https://doi.org/10.2478/10004-1254-61-2010-1976
P. Cvjetko, I. Cvjetko i M. Pavlica, "Thallium Toxicity in Humans", Arhiv za higijenu rada i toksikologiju, vol.61, br. 1, str. 111-118, 2010. [Online]. https://doi.org/10.2478/10004-1254-61-2010-1976
Thallium is a naturally occurring trace element, widely distributed in the earth’s crust, but at very low concentrations. It does not have a known biological use and does not appear to be an essential element for life. It has been considered one of the most toxic heavy metals.
Occasionally, there are reports on thallium poisoning as results of suicide or murder attempt or accident. The main threat to humans is through occupational exposure, environmental contamination, and accumulation in food, mainly in vegetables grown on contaminated soil. Increasing use in emerging new technologies and demanding high-tech industry constantly raise concern about exposure risk to all living organisms. Thallium is considered a cumulative poison that can cause adverse health effects and degenerative changes in many organs. The effects are the most severe in the nervous system. The exact mechanism of thallium toxicity still remains unknown, although impaired glutathione metabolism, oxidative stress, and disruption
of potassium-regulated homeostasis may play a role. The lack of data about mutagenic, carcinogenic, or teratogenic effects of thallium compounds in humans calls for further research.
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