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Histomorphological Analysis of the Osteophytic Appositions in Patients with Lumbar Lateral Recess Syndrome

Goran Bajek ; Department of Neurosurgery, Rijeka University Hospital, Rijeka, Croatia
Snježana Bajek ; Department of Anatomy, Rijeka University School of Medicine, Rijeka, Croatia
Sanja Zoričić Cvek ; Department of Anatomy, Rijeka University School of Medicine, Rijeka, Croatia
Dragica Bobinac ; Department of Anatomy, Rijeka University School of Medicine, Rijeka, Croatia
Bruno Splavski ; Department of Neurosurgery, Osijek University Hospital, Osijek, Croatia
Dubravka Šepić Grahovac ; Polyclinic »Interneuron«, Rijeka, Croatia

Puni tekst: engleski, pdf (314 KB) str. 79-84 preuzimanja: 281* citiraj
APA 6th Edition
Bajek, G., Bajek, S., Zoričić Cvek, S., Bobinac, D., Splavski, B. i Šepić Grahovac, D. (2010). Histomorphological Analysis of the Osteophytic Appositions in Patients with Lumbar Lateral Recess Syndrome. Collegium antropologicum, 34 supplement 2 (2), 79-84. Preuzeto s https://hrcak.srce.hr/51634
MLA 8th Edition
Bajek, Goran, et al. "Histomorphological Analysis of the Osteophytic Appositions in Patients with Lumbar Lateral Recess Syndrome." Collegium antropologicum, vol. 34 supplement 2, br. 2, 2010, str. 79-84. https://hrcak.srce.hr/51634. Citirano 20.10.2020.
Chicago 17th Edition
Bajek, Goran, Snježana Bajek, Sanja Zoričić Cvek, Dragica Bobinac, Bruno Splavski i Dubravka Šepić Grahovac. "Histomorphological Analysis of the Osteophytic Appositions in Patients with Lumbar Lateral Recess Syndrome." Collegium antropologicum 34 supplement 2, br. 2 (2010): 79-84. https://hrcak.srce.hr/51634
Harvard
Bajek, G., et al. (2010). 'Histomorphological Analysis of the Osteophytic Appositions in Patients with Lumbar Lateral Recess Syndrome', Collegium antropologicum, 34 supplement 2(2), str. 79-84. Preuzeto s: https://hrcak.srce.hr/51634 (Datum pristupa: 20.10.2020.)
Vancouver
Bajek G, Bajek S, Zoričić Cvek S, Bobinac D, Splavski B, Šepić Grahovac D. Histomorphological Analysis of the Osteophytic Appositions in Patients with Lumbar Lateral Recess Syndrome. Collegium antropologicum [Internet]. 2010 [pristupljeno 20.10.2020.];34 supplement 2(2):79-84. Dostupno na: https://hrcak.srce.hr/51634
IEEE
G. Bajek, S. Bajek, S. Zoričić Cvek, D. Bobinac, B. Splavski i D. Šepić Grahovac, "Histomorphological Analysis of the Osteophytic Appositions in Patients with Lumbar Lateral Recess Syndrome", Collegium antropologicum, vol.34 supplement 2, br. 2, str. 79-84, 2010. [Online]. Dostupno na: https://hrcak.srce.hr/51634. [Citirano: 20.10.2020.]

Sažetak
Patients with lumbar lateral recess syndrome (LRS) can be successfully cured by removing osseous excrescences that grow on the peripheral edge of articular surface of the facet joint. They cause narrowing of the lateral recess and compress a root of the spinal nerve. Their appearance is related to the instability of respective dynamic vertebral segment. The aim of this study was to analyze the osteophytic composition morphohistochemically and elucidate cellular processes that lead to this new formation appearance. It is necessary to find a possible causative-consequential relation between the osteophyte and instability. The ideal object to explore was the osteophyte in the lateral recess because it had to be removed during operative treatment. The group of 30 patients with clinical feature of LRS was chosen. Each patient had clinically verified LRS with consequential radiculopathy. Bony outgrowths were removed surgically and analyzed by histological and immunohistochemical methods: toluidine blue, Goldner trichrome, TRAP, indirect peroxidase with antibodies against BMP 3 and BMP 7. The outgrowths that caused lateral recess stenosis were composed of fibrous and hyaline cartilage and cancellous bone. The changes in cartilage and bone, and occurrence of intramembranous bone formation in sense of enlargement of trabeculae, leads to the conclusion that marginal osteophytic formations could be an adaptation to changed conditions in the dynamic vertebral segment and an attempt to stabilize this segment by enlargement of articular surface.

Ključne riječi
lumbar lateral recess syndrome; osteophyte; instability; intramembranous bone formation

Hrčak ID: 51634

URI
https://hrcak.srce.hr/51634

Posjeta: 526 *