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The paraoxonase 1, 2 and 3 in humans

Marija Grdic Rajkovic ; Department of Medical Biochemistry and Hematology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia
Lada Rumora ; Department of Medical Biochemistry and Hematology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia
Karmela Barisic ; Department of Medical Biochemistry and Hematology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia

Puni tekst: engleski, pdf (165 KB) str. 122-130 preuzimanja: 406* citiraj
APA 6th Edition
Grdic Rajkovic, M., Rumora, L. i Barisic, K. (2011). The paraoxonase 1, 2 and 3 in humans. Biochemia Medica, 21 (2), 122-130. Preuzeto s https://hrcak.srce.hr/69654
MLA 8th Edition
Grdic Rajkovic, Marija, et al. "The paraoxonase 1, 2 and 3 in humans." Biochemia Medica, vol. 21, br. 2, 2011, str. 122-130. https://hrcak.srce.hr/69654. Citirano 17.09.2019.
Chicago 17th Edition
Grdic Rajkovic, Marija, Lada Rumora i Karmela Barisic. "The paraoxonase 1, 2 and 3 in humans." Biochemia Medica 21, br. 2 (2011): 122-130. https://hrcak.srce.hr/69654
Harvard
Grdic Rajkovic, M., Rumora, L., i Barisic, K. (2011). 'The paraoxonase 1, 2 and 3 in humans', Biochemia Medica, 21(2), str. 122-130. Preuzeto s: https://hrcak.srce.hr/69654 (Datum pristupa: 17.09.2019.)
Vancouver
Grdic Rajkovic M, Rumora L, Barisic K. The paraoxonase 1, 2 and 3 in humans. Biochemia Medica [Internet]. 2011 [pristupljeno 17.09.2019.];21(2):122-130. Dostupno na: https://hrcak.srce.hr/69654
IEEE
M. Grdic Rajkovic, L. Rumora i K. Barisic, "The paraoxonase 1, 2 and 3 in humans", Biochemia Medica, vol.21, br. 2, str. 122-130, 2011. [Online]. Dostupno na: https://hrcak.srce.hr/69654. [Citirano: 17.09.2019.]

Sažetak
The paraoxonase gene family in humans includes three members: PON1, PON2 and PON3. The pro-ducts of those three genes are the following enzymes: paraoxonase 1 (PON1), paraoxonase 2 (PON2) and paraoxonase 3 (PON3). PON1 is mainly associated with a high density lipoprotein (HDL). A small amount of this enzyme is also bound to very low-density lipoprotein (VLDL) and postprandial chylomicrons. PON1 possess organophosphatase, arylesterase and lactonase activity and it hydrolyzes many different substrates. It is also known that PON1 may have antiatherogenic function. Compared to the PON1, PON2 and PON3 are much less studied and described. PON2 is ubiquitously expressed intracellular protein, while PON3 is bound to HDL, like PON1. The both enzymes possess antioxidant properties.

Ključne riječi
paraoxonase 1; paraoxonase 2; paraoxonase 3

Hrčak ID: 69654

URI
https://hrcak.srce.hr/69654

Posjeta: 649 *