Izvorni znanstveni članak
Comparison of peritonsillar infiltration effects of ketamine and tramadol on post tonsillectomy pain: a doubleblinded randomized lacebocontrolled clinical trial
Vida Ayatollahi
; Department of anesthesiology and critical care, Sahid Sadoughi Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Shekoufeh Behdad
; Department of anesthesiology and critical care, Sahid Sadoughi Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Maryam Hatami
; Department of anesthesiology and critical care, Sahid Sadoughi Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Hossein Moshtaghiun
; Department of anesthesiology and critical care, Sahid Sadoughi Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Behnam Baghianimoghadam
; Research consultant, Yazd, Iran
Sažetak
Aim To assess the effect of peritonsillar infiltration of ketamine
and tramadol on post tonsillectomy pain and compare
the side effects.
Methods The double-blind randomized clinical trial was
performed on 126 patients aged 5-12 years who had been
scheduled for elective tonsillectomy. The patients were
randomly divided into 3 groups to receive either ketamine,
tramadol, or placebo. They had American Society of Anesthesiologists
physical status class I and II. All patients underwent
the same method of anesthesia and surgical procedure.
The three groups did not differ according to their
age, sex, and duration of anesthesia and surgery. Post operative
pain was evaluated using CHEOPS score. Other parameters
such as the time to the first request for analgesic,
hemodynamic elements, sedation score, nausea, vomiting,
and hallucination were also assessed during 12 hours after
surgery.
Results Tramadol group had significantly lower pain
scores (P = 0.005), significantly longer time to the first request
for analgesic (P = 0.001), significantly shorter time to
the beginning of liquid regimen (P = 0.001), and lower hemodynamic
parameters such as blood pressure (P = 0.001)
and heart rate (P = 0.001) than other two groups. Ketamine
group had significantly greater presence of hallucinations
and negative behavior than tramadol and placebo groups.
The groups did not differ significantly in the presence of
nausea and vomiting.
Conclusion Preoperative peritonsillar infiltration of tramadol
can decrease post-tonsillectomy pain, analgesic consumption,
and the time to recovery without significant
side effects.
Ključne riječi
Hrčak ID:
83875
URI
Datum izdavanja:
15.4.2012.
Posjeta: 1.394 *