Ostalo
Generalized Perforating Granuloma Annulare: Case Report
Joana Alexandra Devesa Parente
; Department of Dermatology Santarém District Hospital EPE Avenida Bernardo Santareno Apartado 115 2000-153 Santarém Portugal
José Alberto Machado Dores
João Manuel Pires Aranha
Sažetak
We report a case of a 26-year-old Caucasian male presented
with 8-month history of asymptomatic erythematous papulonodular lesions
symmetrically located on the face, trunk and limbs. Histopathologic
examination revealed granulomas with histiocytes arranged in a palisading
pattern around the foci of necrobiotic collagen with mucin deposition,
and transepidermal and transfollicular elimination of degenerated collagen
bundles. These histopathologic findings were compatible with perforating
granuloma annulare. Three months later, the patient was admitted with the
diagnosis of sepsis secondary to a gastroenteritis dyeing on the fourth day
of presentation. Serologic tests for antibody to human immunodeficiency
virus (HIV) performed at this time were positive establishing the diagnosis
of acquired immunodeficiency syndrome (AIDS). Atypical variants of granuloma
annulare including perforating types might be associated with AIDS.
The course and presentation of granuloma annulare might be modified by
disruption of both antigen presentation and effector cell mechanisms in
the HIV-infected patient.
Ključne riječi
perforating granuloma annulare; human immunodeficiency virus
Hrčak ID:
95700
URI
Datum izdavanja:
11.1.2013.
Posjeta: 791 *