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Aggressive Multifocal Form of Epithelioid Hemangioendothelioma – Case Report

Antica Duletić-Načinović
Dragana Grohovac
Renata Dobrila-Dintinjana
Nada Brnčić
Nives Jonjić

Puni tekst: engleski pdf 166 Kb

str. 289-293

preuzimanja: 295



Epithelioid hemangioendothelioma (EHE) is a rare tumor of the vascular origin. It was first described in its pulmonary
form by Dail and Leibow in 1975. and named »intravascular bronhioalveolar tumor« (IVBAT). Since then, reports
of occurences of the tumor have been made for number of locations, but most often tumor can be found in soft tissues,
liver, lungs, bone and skin. It is considered to be a low or borderline malignant tumor with, usually, slow progression,
but aggressive forms have been descrided.We here report a case of a 46-year old female patient with multifocalmalignant
tumor spreading to lungs, liver, spleen and with synchronous involvement of lumbal vertebrae, illiac bones and central
nervous system dissemination. To the best of the authors knowledge, no case of malignant EHE with multiorgan involvement
of this proportions and synchronous central nervous system and bone involvement in one patient has been reported
to this date in English-speaking literature.

Ključne riječi

epithelioid hemangioendothelioma, malignant tumor, metastatic spread

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