Medica Jadertina, Vol. 42 No. 1-2, 2012.
Stručni rad
Schonlein-Henoch Syndrome in children and adolescents: epidemiologic data and coagulation disturbances
Srđana Čulić
; KBC Split, Klinika za pedijatriju, Sveučilište u Splitu, Škola medicine, Split
Željana Čukušić
; Sveučilište u Splitu, Škola medicine, Split, HRVATSKA
Marijan Saraga
; Sveučilište u Splitu, Škola medicine
Branka Pauković-Sekulić
; Odjel kliničkog laboratorija i dijagnostike, Križine, Split, HRVATSKA
Dubravka Kuljiš
; Sveučilište u Splitu, Škola medicine, Split, Hrvatska
Vitomir Metličić
; Sveučilište u Splitu, Škola medicine, Split, Hrvatska
Jasminka Pavelić
; Institut "Ruđer Bošković" Zagreb, Odjel za molekularnu medicinu
Sažetak
The aim of the study was to examine the function of platelets in children and adolescents with Schönlein-Henoch Syndrome (SHS) presenting normal platelet count, and epidemiologic data. The most frequent SHS localization was the skin and joints. The most consistent defect in latelet aggregation was a block of the release of endogenous ADP when ADP was used as induction agent. In conclusion, our epidemiological data differ slightly from those observed by other authors. However, we have shown that increased tendency toward bleeding in SHS might be caused by function disturbances of platelets.
Ključne riječi
SHS; epidemiology; platelet function, thrombocites
Hrčak ID:
83975
URI
Datum izdavanja:
4.6.2012.
Posjeta: 1.891 *