Medicus, Vol. 21 No. 1_UGI, 2012.
Pregledni rad
Benign Prostatic Hyperplasia and Lower Urinary Tract Symptoms
Ivica Mokos
; KBC Zagreb
Sažetak
Benign prostatic hyperplasia is considered a normal part of the aging process in men and is hormonally dependent on dihydrotestosterone production. The voiding dysfunction that results from prostate gland enlargement and bladder outlet obstruction is termed lower urinary tract symptoms (LUTS). Clinical manifestations of LUTS include urinary frequency, urgency, nocturia, decreased or intermittent force of stream, or a sensation of incomplete emptying. The risk of acute urinary retention (AUR) and the need for surgical treatment increase with age. Patients with mild LUTS should be managed with lifestyle advice and pelvic floor muscle exercise. Alpha-blockers should be offered as a first-line treatment to men with bothersome LUTS who request treatment. Treatment with combined alpha-blocker and 5-alpha-reductase inhibitor therapy can significantly reduce the risk of disease progression and avoid long-term complications such as acute urinary retention and surgery. Surgery is appropriate for patients with moderate to severe LUTS who have not responded to drug treatment, or who have developed AUR or any absolute indication for surgery.
Ključne riječi
prostatic hyperplasia; lower urinary tract symptoms; treatment guidelines
Hrčak ID:
89352
URI
Datum izdavanja:
23.1.2012.
Posjeta: 4.733 *