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The Design and Scale-Up of Multiple-Impeller Fermenters for Liquid Film Controlled

L. Labík ; Institute of Chemical Technology Prague, Chemical Engineering Dept., Technická 5, 166 28 Prag 6, Republika Češka
T. Moucha ; Institute of Chemical Technology Prague, Chemical Engineering Dept., Technická 5, 166 28 Prag 6, Republika Češka
M. Kordač ; Institute of Chemical Technology Prague, Chemical Engineering Dept., Technická 5, 166 28 Prag 6, Republika Češka


Puni tekst: engleski pdf 953 Kb

str. 147-158

preuzimanja: 601

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Sažetak

Mechanically agitated gas-liquid contactors are frequently used in the chemical, food and biochemical industries as fermenters and as hydrogenation or chlorination reactors. However wide is the usage of such vessels, their design is not based on chemical engineering data, but is still rather empirical. Thus, it is highly desirable to have a tool for the rational design of agitated gas-liquid contactors that is based on fundamental chemical engineering parameters that are transferable to other systems and operating conditions. Focusing on liquid film-controlled processes and using the data from fermenters of different scales, we develop kLa correlations that are suitable for scale-up.
First, we discuss how to determine the proper experimental kLa values, which are not distorted by other equipment parameters as is the gas residence time. We demonstrate the possible kLa distortion on the pilot-plant experimental data by comparing the results obtained by two different experimental techniques. Further, we present physically correct kLa data for fully non-coalescent (sodium sulphate solution) batch. The data are presented both for laboratory and pilot-plant fermenters. We identify the process parameters, the values of which are dependent on the vessel scale when operated under the same power input per volume, and, using these parameters, we develop common kLa correlations suitable to describe the data for various scales of the vessel. The correlations developed reduce the uncertainty in predicting the volume of industrial scale fermenters from almost 1/2 to 1/4 of their total volume, thereby enabling significant reductions in both the initial costs, and operating costs.



Ključne riječi

Fermenter; mass transfer; mass transfer correlations; mixing; multiple-impeller; scale-up; volumetric mass transfer coefficient

Hrčak ID:

101553

URI

https://hrcak.srce.hr/101553

Datum izdavanja:

9.5.2013.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.229 *