Pregledni rad
https://doi.org/10.3325/cmj.2013.54.219
Use of concentrated bone marrow aspirate and platelet rich plasma during minimally invasive decompression of the femoral head in the treatment of osteonecrosis
John R. Martin
; Department of Orthopedic Surgery, Mayo Clinic Rochester, MN, USA
Matthew T. Houdek
; Department of Orthopedic Surgery, Mayo Clinic Rochester, MN, USA
Rafael J. Sierra
; Department of Orthopedic Surgery, Mayo Clinic Rochester, MN, USA
Sažetak
ABSTRACT The aim of this paper is to describe our surgical
procedure for the treatment of osteonecrosis of the femoral
head using a minimally invasive technique. We have
limited the use of this procedure for patients with pre-collapse
osteonecrosis of the femoral head (Ficat Stage I or II).
To treat osteonecrosis of the femoral head at our institution
we currently use a combination of outpatient, minimally
invasive iliac crest bone marrow aspirations and blood
draw combined with decompressions of the femoral head.
Following the decompression of the femoral head, adult
mesenchymal stem cells obtained from the iliac crest and
platelet rich plasma are injected into the area of osteonecrosis.
Patients are then discharged from the hospital using
crutches to assist with ambulation. This novel technique
was utilized on 77 hips. Sixteen hips (21%) progressed to
further stages of osteonecrosis, ultimately requiring total
hip replacement. Significant pain relief was reported in
86% of patients (n = 60), while the rest of patients reported
little or no pain relief. There were no significant complications
in any patient. We found that the use of a minimally
invasive decompression augmented with concentrated
bone marrow and platelet rich plasma resulted in significant
pain relief and halted the progression of disease in a
majority of patients
Ključne riječi
Hrčak ID:
104754
URI
Datum izdavanja:
15.6.2013.
Posjeta: 1.417 *