Stručni rad

Antisynthetase syndrome - a case report

Višnja Prus ; Klinika za unutarnje bolesti, Klinički bolnički centar Osijek, Osijek, Hrvatska
Dražen Bedeković ; Klinika za unutarnje bolesti, Klinički bolnički centar Osijek, Osijek, Hrvatska
Jasminka Milas-Ahić ; Klinika za unutarnje bolesti, Klinički bolnički centar Osijek, Osijek, Hrvatska
Roberta Višević ; Klinika za unutarnje bolesti, Klinički bolnički centar Osijek, Osijek, Hrvatska
Branko Šegec ; Klinika za unutarnje bolesti, Klinički bolnički centar Osijek, Osijek, Hrvatska
Zlatica Jukić ; Odjel za dermatovenerologiju, Klinika za dermatologiju i venerologiju, Klinički bolnički centar Osijek, Osijek, Hrvatska
Ljiljana Perić ; Klinika za infektologiju, Klinički bolnički centar Osijek, Osijek, Hrvatska

Sažetak

Twenty-eight year-old woman with predominant signs of polymyositis, pulmonary interstitium involvement and with positive anti-Jo1 antibodies was suspected for antisynthetase syndrome. Over the next three months sores and ulcerations have appeared at the fingertips. In the later course of the disease clinical picture of mixed connective tissue disease associated with interstitial lung disease, with a dominant picture of systemic sclerosis have emerged. She was treated with glucocorticoides and immunosuppressive therapy. Patient condition was mostly stable, without significant progression of lung lesions. Early diagnosis and treatment antisynthetase syndrome significantly contributes to more favorable course and outcome of disease. A prerequisite for that are well-defined diagnostic criteria and an appropriate choice of treatment.

Ključne riječi

antisynthetase syndrome; polymyositis; dermatomyositis; mixed connective tissue disease; anti-Jo1 antibody

Hrčak ID:

123594

URI

https://hrcak.srce.hr/123594

Datum izdavanja:

1.6.2013.

Podaci na drugim jezicima: hrvatski

Posjeta: 3.865 *