Reumatizam, Vol. 56 No. 1, 2009.
Uvodnik
The clinical picture of rheumatoid arthritis - the complex of three independent mechanisms
Hans Georg Fassbender
; Centar za patologiju reumatskih bolesti Sveučilišnih klinika “Johannes Gutenberg”, Mainz, Njemačka
Carola Meyer-Scholten
; Centar za patologiju reumatskih bolesti Sveučilišnih klinika “Johannes Gutenberg”, Mainz, Njemačka
Kati Zorn
; Centar za patologiju reumatskih bolesti Sveučilišnih klinika “Johannes Gutenberg”, Mainz, Njemačka
Sažetak
The assumption of inflamation as the only cause of the complex clinical picture of rheumatoid atrhritis does not correspond to facts. We have found and proven the existence of three seemingly unconnected mechanisms, and only their combination can account for the general clinical picture of rheumatoid arthritis. They are: 1. immunologic synovitis, responsible for pain, swelling and stiffnes; 2. oncological process (“tumor-like proliferation”), responsible for the destruction of joints; 3. Primary necrotizing process, responsible for the (sometimes lethal) destructions in the heart and blood vessels.
Ključne riječi
rheumatoid arthritis; synovitis; tumor-like proliferation; primary necrotizing process
Hrčak ID:
125214
URI
Datum izdavanja:
1.7.2009.
Posjeta: 2.170 *