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Oxidation Induced Changes in Lipid Mobility in Lipoproteins Followed by Steady State Fluorescence Anisotropy

Jasminka Brnjas-Kraljević ; School of Medicine, University of Zagreb, Zagreb, Croatia
Greta Pifat-Mrzljak ; Ruđer Bošković Institute, Zagreb, Croatia
Gabrielle Knipping ; Institute for Medical Biochemistry, University of Graz, Graz, Austria
Gunther Jurgens ; Institute for Medical Biochemistry, University of Graz, Graz, Austria


Puni tekst: engleski pdf 3.974 Kb

str. 679-687

preuzimanja: 247

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Sažetak

The oxidation induced changes in the lipid layer of the lipoprotein
particles of LDL and HDLs have been followed by measuring the
steady-state polarization anisotropy of the fluorescence probe
TMA-DPH incorporated in the lipid layer. The mobility restriction
gradually increases with oxidation in LDL and HDL2 indicating the oxidation-induced structuring of lipids, while the effect of oxidation
in HDL3 is negligible.

Ključne riječi

Hrčak ID:

176966

URI

https://hrcak.srce.hr/176966

Posjeta: 390 *