Cardiologia Croatica, Vol. 12 No. 7-8, 2017.
Stručni rad
https://doi.org/10.15836/ccar2017.311
Kidney Disease and Obesity.
Dubravka Mihaljević
orcid.org/0000-0002-0051-4154
; Sveučilište Josipa Jurja Strossmayera u Osijeku, Medicinski fakultet Osijek, Klinički bolnički centar Osijek, Osijek, Hrvatska
Sažetak
Obesity is a global problem and a serious chronic disease. Some non-communicablediseases, includingobesity are among the leadingcauses of morbidity and mortality globally. Obesity is associated with a variety of disorders and diseases that have direct impact on kidney function. This primarily refers to diabetes mellitus, elevated arterial pressure, and metabolic syndrome. Obesity, even without associated diseases, favors development of chronic kidney disease (CKD). Obesity is associated with a number of kidney diseases such as glomerulopathies and nephrolithiasis, and influences kidney graft survival. Metabolic syndrome and diabetes mellitus type 2 are classic risk factors for CKD and cardiovascular disease development. Inflammation is one of the most important CKD and obesity characteristics, contributing to the development of glomerulosclerosis and tubulointerstitial atrophy. Along with glomerulopathy associated with obesity, focal segmental glomerulosclerosis with significant proteinuria is directly related to obesity. Adipose patients with IgA nephropathy have poorer disease prognosis.
Ključne riječi
obesity; chronic kidney disease; glomerulopathy associated with obesity
Hrčak ID:
185344
URI
Datum izdavanja:
21.7.2017.
Posjeta: 1.368 *