Croatica Chemica Acta, Vol. 35 No. 4, 1963.
Izvorni znanstveni članak
Synthetic Studies in the Chloramphenicol Series. VI. Synthesis of DL - threo-1-p-nitrophenyl-1 -hydroxy-2-dichloroacetamido-3- methylsulfinyl and 3-methylsulfonyl propane
M. Fleš
; Research Department, »Pliva« Pharmaceutical and Chemical Works, Zagreb, Croatia, Yugoslavia
Sažetak
The compounds mentioned in the title were prepared from
a.-phthalimido-~-methylmercaptopropiophenone (I). Reduction of
I with aluminium isopropoxide gave preferentially the threo carbinol
II which upon acetylation and subsequent nitration gave
a mixture of diastereomeric sulfoxides which were oxidized with
hydrogen peroxide to the identical sulfones.
Ključne riječi
Hrčak ID:
208323
URI
Datum izdavanja:
28.2.1964.
Posjeta: 759 *