Skoči na glavni sadržaj

Izvorni znanstveni članak

Studies in the Sphingolipids Series. XXIII. Synthesis and Resolution of erythro and threo "'C20-Sphingosines

B. Majhofer-Oreščanin ; Department of Biochemistry, Institute »Ruder Bo!ikovic«, Zagreb, Croatia, Yugoslavia
M. Proštenik ; Department of Biochemistry, Institute »Ruder Bo!ikovic«, Zagreb, Croatia, Yugoslavia


Puni tekst: engleski pdf 7.260 Kb

str. 161-166

preuzimanja: 56

citiraj


Sažetak

The synthesis of DL-trans-2-amino-11,3-dihydroxy-4-eicosenes (VII)
by condensation of 2-octadecyne-1- al (IV) with nitroethanol in ihe
presence of potassium carbonate and subsequent reduction of the
two nitrodiols (V) is described. The resolution of the DL-threo - base
(VIIa) into the optical isomers was effected with D-tartaric acid.
The DL - erythro-base (VIIb) was resolved with L-glutamic acid.
N atural C20-sphingosine i s most probably the trans-D( -t-) - erythrobase.

Ključne riječi

Hrčak ID:

208395

URI

https://hrcak.srce.hr/208395

Posjeta: 113 *