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THE DIFFERENCE IN TIME UNTIL THE APPEARANCE OF RECIDIVE OR METASTASIS MANIFESTATION AT PATIENTS CURED AGAINST COLORECTAL CANCER DEPENDING ON THE POSITION IN THE LEFT OR RIGHT COLON

Darko Kotromanović orcid id orcid.org/0000-0001-9594-4650 ; Klinički bolnički centar Osijek, Josipa Huttlera 4, Osijek, Republika Hrvatska


Puni tekst: hrvatski pdf 292 Kb

str. 30-30

preuzimanja: 245

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Puni tekst: engleski pdf 292 Kb

str. 31-31

preuzimanja: 244

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Sažetak

Introduction: The purpose of the study was to determine the difference in time until the appearance of relapse or metastases in patients treated for colorectal cancer, depending on the location of the tumor in the left or right colon at the Oncology Clinic of Clinical Medical Centre Osijek between 2010 and 2012, including 2012.
Methods: Study includes respondents whose data were taken from medical archive at the Oncology Clinic of Clinical Medical Centre Osijek. The data on patients' deaths were taken from the Registry Office of the Republic of Croatia.
Results: The study included 272 patients, 160 (58.8%) men and 112 (41.2%) women. According to the location, left sided colon tumor was discovered in 211 (77.6%) patients and right-sided in 61 (22.4%). The median age of patients was 67 years. Right-sided colon tumors are considerably larger with median diameter of 6 cm, as well as the number of lymph nodes, with median number of 16 cm. Median of time until the appearance of the metastases is 20 months (interquartile range is from 8 to 29 months); marked time being shorter in right-sided colon tumors. Positive outcome of the treatment was achieved in 205 (75.4%) patients, with no significant difference in comparison to the colon cancer localization. By using Kaplan-Meier analysis of patients' survival rates, a total 5- year survival rate of 72% was achieved in right-sided colon tumor in comparison to 62% in patients with the left-sided colon tumor.
Conclusion: This study confirms that there is a difference in colorectal cancer according to its location. Patients with right-sided colorectal cancer are older, the carcinoma is larger, the time until the appearance of a relapse or a metastases is shorter and 5-year survival rate is lower.

Ključne riječi

colorectal cancer; oncology; colon

Hrčak ID:

218609

URI

https://hrcak.srce.hr/218609

Datum izdavanja:

31.12.2018.

Podaci na drugim jezicima: hrvatski

Posjeta: 2.170 *