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https://doi.org/10.15255/KUI.2019.032

3D-Printed Oral Dosage Forms Loaded with Dispersion of Oil and Active Ingredient

Andrea Milićević ; Fakultet kemijskog inženjerstva i tehnologije, Sveučilište u Zagrebu, Marulićev trg 19, 10 000 Zagreb
Matija Gretić orcid id orcid.org/0000-0002-6895-229X ; Fakultet kemijskog inženjerstva i tehnologije, Sveučilište u Zagrebu, Marulićev trg 19, 10 000 Zagreb
Gordana Matijašić orcid id orcid.org/0000-0002-8521-2154 ; Fakultet kemijskog inženjerstva i tehnologije, Sveučilište u Zagrebu, Marulićev trg 19, 10 000 Zagreb


Puni tekst: hrvatski pdf 1.146 Kb

str. 389-396

preuzimanja: 403

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Sažetak

In this study, the possibility of producing pharmaceutical dosage forms by 3D printing technology is examined. In vitro dissolution tests were performed with printed dosage forms, and the results analysed in Microsoft Excel Add-In, DDSolver. 3D printing has provided six different models of solid dosage forms. The results of dissolution test have shown release profiles with initial time delay. The profiles are described by the Peppas-Sahlin model. It is shown that 3D printing technology has the potential to become a method for quick and simple production of personalized dosage forms with delayed release.


This work is licensed under a Creative Commons Attribution 4.0 International License.

Ključne riječi

3D print; personalized medicines; delayed release; release profiles; Peppas-Sahlin model

Hrčak ID:

225282

URI

https://hrcak.srce.hr/225282

Datum izdavanja:

7.10.2019.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.598 *