Acta clinica Croatica, Vol. 59. No. 1., 2020.
Original scientific paper
https://doi.org/10.20471/acc.2020.59.01.10
Predictors of Early-Onset Depression after First-Ever Stroke
Tamara Rabi-Žikić
; Department of Neurology, Clinical Centre of Vojvodina, Novi Sad, Serbia; University of Novi Sad, Faculty of Medicine, Department of Neurology, Novi Sad, Serbia
Željko Živanović
; Department of Neurology, Clinical Centre of Vojvodina, Novi Sad, Serbia; University of Novi Sad, Faculty of Medicine, Department of Neurology, Novi Sad, Serbia
Vlado Đajić
; Department of Neurology, Clinical Centre of Republic of Srpska, Banjaluka, Republic of Srpska, Bosnia and Herzegovina; University of Banjaluka, Faculty of Medicine, Banjaluka, Republic of Srpska, Bosnia and Herzegovina
Svetlana Simić
; Department of Neurology, Clinical Centre of Vojvodina, Novi Sad, Serbia; University of Novi Sad, Faculty of Medicine, Department of Neurology, Novi Sad, Serbia
Svetlana Ružička-Kaloci
; Department of Neurology, Clinical Centre of Vojvodina, Novi Sad, Serbia; University of Novi Sad, Faculty of Medicine, Department of Neurology, Novi Sad, Serbia
Sonja Slankamenac
; Department of Endocrinology, Diabetes and Metabolic Diseases, Clinical Centre of Vojvodina, Novi Sad, Serbia
Milorad Žikić
; Global Prevent, Institute for Occupational Health, Novi Sad, Serbia
Abstract
Post-stroke depression (PSD) is a severe and frequent stroke complication and one of the crucial factors for the outcome of rehabilitation and life quality after stroke. However, mood disorders frequently remain unnoticed and therefore untreated. The aim of the study was to examine all the potential risk factors and determine the independent predictors of early-onset depression after first-ever stroke, which would help identify high-risk patients, establish early diagnosis and timely treatment that would improve the course and prognosis of this disorder. This prospective study included 60 patients treated for their first-ever stroke; there were 30 patients diagnosed with depression and 30 patients without depression. The study included collection and analysis of all socio-demographic and clinical risk factors for PSD. Testing was performed two weeks after stroke. Depression
was diagnosed according to the Mini International Neuropsychiatry Interview, DSM-IV diagnostic criteria, and depression severity was quantified by the Hamilton Depression Rating Scale. Cognitive
impairment was assessed by the Mini Mental State Examination. Neurological deficit was assessed by the US National Institute of Health Stroke Scale. Our results showed that the independent predictors of early-onset depression after stroke were previous depressive episodes, cognitive dysfunction, and more severe neurological deficit.
Keywords
Stroke; Depression; Quality of life; Mood disorders; Risk factors; Early diagnosis
Hrčak ID:
242271
URI
Publication date:
1.3.2020.
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