Pregledni rad

https://doi.org/10.20471/acc.2020.59.04.20

The Use of Electroretinography and Optical Coherence Tomography in Patients with Schizophrenia

Din Duraković ; Sestre milosrdnice University Hospital Centre, Department of Psychiatry, Zagreb, Croatia
Ante Silić orcid.org/0000-0003-2840-8836 ; Sestre milosrdnice University Hospital Centre, Department of Psychiatry, Zagreb, Croatia; Catholic University of Croatia, Zagreb, Croatia
Vjekoslav Peitl orcid.org/0000-0003-4163-6411 ; Sestre milosrdnice University Hospital Centre, Department of Psychiatry, Zagreb, Croatia; Catholic University of Croatia, Zagreb, Croatia
Rašeljka Tadić ; Sestre milosrdnice University Hospital Centre, Department of Ophthalmology, Zagreb, Croatia
Kristina Lončarić ; Sestre milosrdnice University Hospital Centre, Department of Ophthalmology, Zagreb, Croatia
Trpimir Glavina ; Sestre milosrdnice University Hospital Centre, Department of Psychiatry, Zagreb, Croatia
Daniela Šago ; Sestre milosrdnice University Hospital Centre, Department of Psychiatry, Zagreb, Croatia
Ljiljana Pačić Turk orcid.org/0000-0002-5276-0330 ; Catholic University of Croatia, Zagreb, Croatia
Dalibor Karlović orcid.org/0000-0001-6538-7240 ; Sestre milosrdnice University Hospital Centre, Department of Psychiatry, Zagreb, Croatia; Catholic University of Croatia, Zagreb, Croatia

Sažetak

The use of electroretinography (ERG) and optical coherence tomography (OCT)
has currently expanded beyond ophthalmology alone. The aim of this review is to present the results
and knowledge acquired by these two methods in patients suffering from schizophrenia. Reviewing
the studies applying ERG and OCT methods in the field of psychiatry, one can conclude that results
of the research imply morphological and functional changes of retina in patients with schizophrenia
that are not consistent. However, in most studies there was reduction of the amplitude and changes in
the implicit time related parameters on ERG and thinning of the retinal nerve fiber layer on OCT.
Neurons in the eye use the same neurotransmitters as neurons in the basal brain structures that are
most affected in schizophrenia, according to the dopamine hypothesis of schizophrenia. Unlike neurons
in the basal brain structures, the neurons in the eye are in vivo available to ERG. Using the
aforementioned tests together with clinical diagnostic criteria of schizophrenia, the subgroups with
different prognostic and therapeutic specificities within schizophrenia as a group of diseases might be
identified more precisely.

Ključne riječi

Schizophrenia; Electroretinography; Optical coherence tomography; Neuroophthalmology

Hrčak ID:

254898

URI

https://hrcak.srce.hr/254898

Datum izdavanja:

1.12.2020.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.360 *