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Gynaecologia et perinatologia : : časopis za ginekologiju, perinatologiju, reproduktivnu medicinu i ultrazvučnu dijagnostiku, Vol. 15 No. 3, 2006.

Stručni rad

PLACENTAL ALKALINE PHOSPHATASE AS A BIOCHEMICAL MARKER OF IDIOPATHIC PRETERM DELIVERY

Gordana Grgić ; Klinika za ginekologiju i akušerstvo, Univerzitetsko Klinički centar, Medicinski fakultet, Tuzla
Zlatan Fatušić ; Klinika za ginekologiju i akušerstvo, Univerzitetsko Klinički centar, Medicinski fakultet, Tuzla
Nijaz Tihić ; Zavod za mikrobiologiju, Univerzitetsko Klinički centar i Medicinski fakultet, Tuzla
Lejla Begić ; Medicinski fakultet Tuzla
Gordana Bogdanović ; Klinika za ginekologiju i akušerstvo, Univerzitetsko Klinički centar i Medicinski fakultet, Tuzla
Fahrija Skokić ; Klinika za ginekologiju i akušerstvo, Univerzitetsko Klinički centar i Medicinski fakultet, Tuzla

Puni tekst: hrvatski pdf 65 Kb

str. 162-165

preuzimanja: 2.537

citiraj

Sažetak

Different researches pointed out that human placental alkaline phosphatase (hPIAP) can be used as a possible marker of idiopathic premature labour. Objective. To examine reliability of hPIAP in mothers serum as a marker of premature labour among pregnant women who had no any of known risks for premature labour and to determine critical value of hPIAP in pregnancies which terminated as a premature labour; to establish the relation between hPIAP and ¬newborns of low birth weight. Material and methods. The research is done in a form of prospective study of 150 pregnant women, who have had no known risks factors for premature labour and who have had adequate antenatal care. The value of hPIAP in serum of all pregnant women were determined in period from 20 to 24 weeks of pregnancy. In further course of pregnancy was evaluated does the premature labour occur more frequently in those with increased values of hPIAP in relation to women who had normal values. As a critical for hPIAP was taken the value over two medians (>2M). Results. The number of premature labours was 17 (11.3%). Mean value of hPIAP in pregnant women who delivered prematurely was 1195, while in those who gave birth on time 632.16. The difference is statistically significant (p<0.0001). Value of hPIAP >2M had 29 (19.34%) of women who gave birth prematurely. Conclusion. hPIAP can be used as a reliable marker of idiopathic premature labour in pregnant women who have no risk factor for premature labour. hPIAP values which is related to development of premature labour is 990 mU/l.

Ključne riječi

preterm labour; placental alkaline phosphatase

Hrčak ID:

23859

URI

https://hrcak.srce.hr/23859

Datum izdavanja:

1.9.2006.

Podaci na drugim jezicima: hrvatski

Posjeta: 4.420 *