Recenzija, Prikaz slučaja

https://doi.org/10.20471/acc.2021.60.01.19

Unusual Clinical Course of Neurosarcoidosis Manifested with Acute Hydrocephalus

Dragana Jovanović ; Medical Faculty, University of Belgrade, Belgrade, Serbia; Department of Pulmonology, Clinical Center of Serbia, Belgrade, Serbia
Dana Grujičić ; Medical Faculty, University of Belgrade, Belgrade, Serbia; Department of Neurosurgery, Clinical Center of Serbia, Belgrade, Serbia
Mihailo Stjepanović ; Medical Faculty, University of Belgrade, Belgrade, Serbia; Department of Pulmonology, Clinical Center of Serbia, Belgrade, Serbia
Spasoje Popević ; Medical Faculty, University of Belgrade, Belgrade, Serbia; Department of Pulmonology, Clinical Center of Serbia, Belgrade, Serbia
Milica Kontić ; Medical Faculty, University of Belgrade, Belgrade, Serbia; Department of Pulmonology, Clinical Center of Serbia, Belgrade, Serbia
Violeta Vučinić Mihailović ; Medical Faculty, University of Belgrade, Belgrade, Serbia; Department of Neurosurgery, Clinical Center of Serbia, Belgrade, Serbia

Sažetak

Approximately 5% to 15% of patients with systemic sarcoidosis develop neurological
complications. However, the actual prevalence of subclinical disease may be higher. Symptoms
are not specific, and may resemble those of other neurological diseases. Hydrocephalus occurs in 6%
of patients with neurosarcoidosis. Acute hydrocephalus is extremely rare and when it occurs, it is usually
difficult to diagnose, thus leading to possible complications. We present a patient who developed
acute hydrocephalus due to neurosarcoidosis, for which he had to be operated on; soon after the operation,
cranial infection developed that required definitive drainage system and ventriculoperitoneal
shunt had to be implanted. In further complicated clinical course, after four years on corticosteroid
therapy (corticosteroid dependent sarcoidosis), he had to be urgently operated on because of significant
ventricular catheter adhesions, but several days after the operation he died in coma because of
progressive brain edema not responding to treatment. As hydrocephalus due to neurosarcoidosis has
high morbidity and mortality, early diagnosis and proper treatment are of utmost importance.

Ključne riječi

Sarcoidosis; Neurosarcoidosis; Hydrocephalus; Treatment

Hrčak ID:

259959

URI

https://hrcak.srce.hr/259959

Datum izdavanja:

1.3.2021.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.825 *