Izvorni znanstveni članak
https://doi.org/10.3325/cmj.2021.62.43 5
Evaluation of colon mucosa using screening colonoscopy and flexible spectral imaging color enhancement in patients with long lasting ulcerative colitis
Seda Akkaya Özdinç
; Department of Gastroenterology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey
Hale Akpinar
; Department of Gastroenterology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey
Göksel Bengi
; Department of Gastroenterology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey
Sülen Sarioğlu
; Department of Pathology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey
Özgül Sağol
; Department of Pathology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey
Gozde Dervis Hakim
; Department of Gastroenterology, Tepecik Education and Research Hospital, İzmir, Turkey
Mesut Akarsu
; Department of Gastroenterology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey
Müjde Soytürk
; Department of Gastroenterology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey
Omer Selahattin Topalak
; Department of Gastroenterology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey
Sažetak
Aim To determine which flexible spectral imaging color
enhancement (FICE) channel best visualizes colon mucosa
in ulcerative colitis (UC) and to compare FICE imaging with
standard imaging.
Methods The study enrolled patients with ulcerative coli
-
tis in remission who had inflammatory bowel disease for
at least 8 years. All patients underwent screening colonos
-
copy. The entire colon, especially the suspicious areas in
terms of dysplasia, were imaged with standard endosco
-
py and FICE. Random and target biopsies were obtained.
Histopathological diagnosis was made and image patterns
were evaluated. Seven endoscopists evaluated normal,
colitis, and polyp images obtained with FICE.
Results One hundred and twenty-three colon segments
were evaluated and 1831 images were obtained from 18
patients. A total of 1652 images were FICE and 179 were
standard images. Separate FICE images were obtained for
normal colon mucosa, polypoid lesions, and colitis areas.
Normal colon mucosa was best visualized using the sec
-
ond, sixth, and ninth FICE channel; polyps using the third,
seventh, and ninth channel; and colitis using the second,
third, and ninth channel. When all images were analyzed,
the second and ninth channel were significantly bet
-
ter than the other channels. A total of 584 biopsies were
obtained, including 492 (84.2%) random biopsies and 92
(15.7%) target biopsies. Random biopsies detected no dys
-
plasia, but target biopsies detected low-grade dysplasia in
three diminutive polyps.
Conclusion FICE was not significantly better at dysplasia
screening than the standard procedure, but it effectively
detected diminutive polyps and evaluated surface pat
-
terns without using magnification. FICE might contribute
to the assessment of inflammation severity in patients with
UC in clinical remission. However, more extensive studies
are necessary to confirm these findings
Ključne riječi
Hrčak ID:
278460
URI
Datum izdavanja:
21.10.2021.
Posjeta: 673 *